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Perianal fistula Crohn's disease is a disease that severely impairs quality of life and affects approximately 30% of patients with ron's disea.
Perianal fistula Crohn's disease is a disease that severely impairs quality of life and affects approximately 30% of patients with ron's disea.
To this end, we conducted a cross-sectional retrospective multicenter stu.
Among 193 patients (infliximab, n=117; adalimumab, n=76), patients with radiation healing had higher median drug levels than those with active disease (infliximab 0 vs 9 μg /mL; adalimumab 1 vs 2 μg/mL; P <.
Figure: Schematic diagram of the correlation between anti-TNF-α levels and radiological findings of Crohn's perianal fistulas
This study demonstrated that higher anti-TNF drug levels were associated with improved radiological outcomes on magnetic resonance imaging in perianal Crohn's disease, with improved outcomes for infliximab and adalimumab in the higher drug level tertiles gradually increa.
Original source:
Michael De Gregor.
