Children's intranasal cells will be "prepared" when "detecting" the new coronavirus

　Children's intranasal cells will be "prepared" when "detecting" the new coronavirus

Or the reason for the milder symptoms in the younger group

Science and Technology Daily, Beijing, August 22 (Reporter Zhang Mengran) A study on new coronary pneumonia published in the British journal Nature Biotechnology on the 19th showed that children’s intranasal epithelium and immune cells are more effective in "detecting" the new coronavirus.

Compared with adults, children not only have a lower risk of severe new coronary pneumonia, but their initial risk of infection is also lower

Roland Ayers, a scientist at the Berlin Institute of Health under the Charité Hospital in Germany, and his colleagues investigated the differences between the genes expressed in the upper respiratory tract cells of children and adults in patients with new coronary pneumonia

Single-cell sequencing revealed that the children's intranasal epithelial cells and immune cells in this study have a higher baseline for specific RNA pattern recognition receptors (such as MDA5 and RIG-I) associated with the "detection" of the new coronavirus

At the same time, nasal samples from these children are more likely to have unique T cell subpopulations

The research team concluded that these findings may enable us to further understand why children are better than adults in the initial stages of controlling new coronavirus infections