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Clin Gastroenterology H: Is anti-tumor necrosis factor therapy still effective for elderly patients with ulcerative colitis?

 Last Update: 2021-05-07
 Source: Internet
 Author: User

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medsci.

Tumor necrosis factor alpha antagonist (anti-TNF) is one of the most effective drugs to induce and maintain moderate to severe UC remission.

The researchers collected clinical data on anti-TNF therapy in UC patients.

infection

The study cohort included a total of 2257 patients (including 231 patients 60 years of age or older).

Figure: The therapeutic effect of anti-TNF preparations on ulcerative colitis

This study confirmed that elderly UC patients received anti-tumor necrosis factor therapy increased the risk of SAE, but there was no difference in the efficacy of anti-TNF therapy between elderly and young patients.

Original source:

David Cheng.

Safety and Efficacy of Tumor Necrosis Factor Antagonists in Older Patients With Ulcerative Colitis: Patient-Level Pooled Analysis of Data From Randomized Trials.
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