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    Home > Active Ingredient News > Digestive System Information > Clin Gastroenterology H: Normalization of fecal calprotectin levels within 12 months of diagnosis of Crohn's disease is associated with reduced risk of disease progression

    Clin Gastroenterology H: Normalization of fecal calprotectin levels within 12 months of diagnosis of Crohn's disease is associated with reduced risk of disease progression

    • Last Update: 2021-09-19
    • Source: Internet
    • Author: User
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    At present, 1 out of every 352 people in the world suffers from Crohn's disease (CD).


    At present, 1 out of every 352 people in the world suffers from Crohn's disease (CD).


     

    The treatment goal of CD is mucosal healing (MH), but the evaluation of MH requires ileocolonoscopy, which is an invasive and expensive examination item that is difficult to implement clinically


    diagnosis

    Researchers conducted a retrospective cohort study at a tertiary IBD center in the United Kingdom and included patients with all CD events diagnosed from 2005 to 2017 in this study


     

    Finally, a total of 375 patients were included in this study, with a median follow-up time of 5.


     Figure: The effect of changes in fecal calprotectin levels on disease recurrence

    Through this retrospective study, the authors confirmed that the normalization of FC in patients with CD within 12 months after diagnosis is associated with a reduced risk of CD progression


    Original source:

    Nikolas Plevris.


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