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Background and targetprevious observational studies of predominantly white populations found that newdiabeteswere associated with an increased risk ofpancreatic cancerThis study attempts to determine whether this relationship applies to other races or races and to determine the metabolic spectrum associated with an increased risk of pancreatic cancermethod
researchers conducted a group-based cohort study of Asian, black, Hispanic and white patients from Southern California hospitals between 2006 and 2016 (n s 1499627)Diabetics were identified based on glucose and hemoglobin A1c (HbA1c) measurements, and Cox regression was used to assess the relationship between diabetes status and course and pancreatic cancerFor patients with recentdiagnosisdiabetes (1 year or less), the researchers compared vertical changes in glucose, HbA1c and weight between diabetes and non-pancreatic cancer patients in the three years between diagnosis and diagnosisresultsfound 2002 cases of pancreatic cancer in nearly 7.5 million years of follow-upThe risk of pancreatic cancer in individuals recently diagnosed with diabetes increased nearly seven folds compared to patients without diabetes (6.91 relative risk; 95% CI was 5.76-8.30) Glucose in patients with recently diagnosed with diabetes (cases: cases, 37.47 mg/dL, 27.68 mg/dL, 27.68 mg/dL) and HbA1c (sbslope: cases, 1.39% compared to non-cases, 0.86% in the month prior to diabetes diagnosis), and minor weight loss in previous years (gradeslope: 0.18 kg/g/interval, non-330 033) Conclusions
this study found an increased risk of pancreatic cancer in patients diagnosed with diabetes of different races and races Rapid developments in weight loss and poor blood sugar control are associated with an increased risk of pancreatic cancer in multiple races