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    Home > Active Ingredient News > Digestive System Information > Clin Nutrition: Early caloric deficit associated with higher risk of death in invasively ventilated COVID-19 patients

    Clin Nutrition: Early caloric deficit associated with higher risk of death in invasively ventilated COVID-19 patients

    • Last Update: 2022-04-22
    • Source: Internet
    • Author: User
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    The 2019 novel coronavirus disease ( COVID-19 ) pandemic has severely impacted healthcare systems around the world and caused large numbers of deaths
    .


    Most patients have mild clinical symptoms and are likely to recover


    The 2019 novel coronavirus disease ( COVID-19 ) pandemic has severely impacted healthcare systems around the world and caused large numbers of deaths


     

    This is a prospective study conducted in the intensive care units (ICUs) of two referral university hospitals in the Italian region of Lombardy during the first pandemic of Covid-19
    .


    During their ICU stay, researchers evaluated 222 continuously mechanically ventilated patients with COVID-19


    statistics

     

    Results of the study showed that among patients who remained in the ICU and survived on day 4 (N = 198), 129 (65.
    2%) and 72 (36.
    4%), respectively, achieved satisfactory caloric and protein intake ( mainly via the enteral route)
    .


    In multivariate analysis, satisfactory caloric intake on day 4 was associated with lower mortality (HR = 0.


    2 2

    Figure: Relationship between invasive ventilation and caloric supplementation in ICU

     

    This study confirms the negative prognostic and clinical role of obesity in mechanically ventilated COVID-19 patients and suggests that early caloric deficit may independently contribute to worse survival in this patient population
    .


    Therefore, every effort should be made to implement adequate and timely nutritional support for all COVID-19 patients during their ICU stay


    This study confirms the negative prognostic and clinical role of obesity in mechanically ventilated COVID-19 patients and suggests that early caloric deficit may independently contribute to worse survival in this patient population


     

    Original source:

    EmanueleCereda.


    Early caloric deficit is associated with a higher risk of death in invasive ventilated COVID-19 patients.
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