Background and target peritina dialysis (PD) are associated with many adverse changes in body composition, including increased fat and muscle loss.
changes in body composition are related to long-term prognosms.
the purpose of this study is to analyze the effects of longitudinal changes in body composition on all-cause mortality in PD patients.
PD patients were tested for bio impedance testing (BIS) and grip force (HGS) at baseline and after 2 years.
131 of the 160 patients received repeated BIS and HGS tests.
loss of the Thin Tissue Index (LTI) and the increase in the Adipose Tissue Index (FTI) were defined as a 10% decrease in LTI and a 10% increase in FTI after 2 years.
then studied changes in body composition over a two-year 2-year err on all patients.
results showed that the prevalence of muscle reduction at baseline was 13.8%.
two years, increases in LTI loss and FTI were observed in patients 40 (30.5%) and 58 (44.3%), respectively.
baseline clinical factors do not predict changes in the vertical composition of the body, and there is a negative correlation between changes in LTI and FTI (r s -0.574, p slt;0.001).
after adjusting demographic and biomeological parameters, low LTI and low HGS at baseline are important predictive indicators of all-cause mortality, but not when cardiovascular factors are included in multi-factor analysis.
, however, ltI loss and FTI gain were independent risk factors for all-cause mortality after adjusting demographic, bio-chemical, and cardiovascular parameters.
in patients with PD, vertical changes in LTI and FTI were associated with all-cause mortality, with loss of lean tissue and increased adipose tissue significantly increasing mortality.