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Primary sclerosing cholangitis (PSC) is a progressive self- immune liver disease, and liver with chronic inflammation and symptoms of extrahepatic biliary stricture, and eventually leading to liver fibrosis and cirrhosis.
Primary sclerosing cholangitis (PSC) is a progressive self- immune liver disease, and liver with chronic inflammation and symptoms of extrahepatic biliary stricture, and eventually leading to liver fibrosis and cirrhosis.
This study included patients from two independent PSC cohorts at the Oslo Medical Center (n = 138) and Helsinki Medical Center (n = 159), and detected the levels of CD163 and sMR in the blood of the patients.
This study included patients from two independent PSC cohorts at the Oslo Medical Center (n = 138) and Helsinki Medical Center (n = 159), and detected the levels of CD163 and sMR in the blood of the patients.
The median (interquartile range) of sCD163 in the Oslo and Helsinki cohorts were 3.
The median (interquartile range) of sCD163 in the Oslo and Helsinki cohorts were 3.
This study confirmed that macrophage activation markers increase due to the severity of the disease, indicating that macrophages play an important role in PSC.
This study confirmed that macrophage activation markers increase due to the severity of the disease, indicating that macrophages play an important role in PSC.
Original source:
Original source:Bossen, Lars .
Bossen, Lars .
E T Al.
lww.
com/ctg/Fulltext/2021/03000/Circulating_Macrophage_Activation_Markers_Predict.
4.
aspx" target="_blank" rel="noopener">Circulating Macrophage Activation-Markers Predict Transplant as Free Survival in Patients With Primary sclerosing cholangitis .
Circulating Macrophage Activation-Markers Predict Transplant as Free Survival in Patients With Primary sclerosing cholangitis .
Clinical Gastroenterology and the Translational .
2021.
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