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Dysphagia refers to a feeling
of obstruction in the pharynxal, retrosternal, or xiphoid part of the food transported from the mouth to the stomach and cardia.
May be accompanied by retrosternal pain
.
Dysphagia can be caused by disorders of the central nervous system, esophagus, oropharynx, or by dyskinesia of the swallowing muscles
.
Dysphagia is more likely to occur in children and the elderly because of their imperfect or degenerative swallowing function, but it is more common due to disease factors and can also be caused by
ingestion of a foreign body.
Disease factors that cause dysphagia are common in the nervous and digestive systems
.
Dysphagia can cause aspiration pneumonia and even asphyxia that is life-threatening, so accurate diagnosis and timely treatment of dysphagia are necessary
.
1.
Symptoms and signs of oral/pharyngeal dysphagia
Coughing or choking when swallowing
Difficulty starting to swallow
Food is blocked in the throat
Salivation
Unexplained weight loss
Changes in eating habits
Recurrent pneumonia
Changes in voice or speech
Transnasal reflux
2.
Symptoms and signs of esophageal dysphagia
Food is blocked in the chest or throat
Changes in eating habits
Recurrent pneumonia
Symptoms of gastroesophageal reflux disease (GERD), including heartburn, belching, acid reflux, and heartburn
3.
Other related factors/symptoms of dysphagia
General weakness
Altered mental status
1.
Oropharyngeal dysphagia
It means that it is difficult for the esophagus to enter the esophagus from the pharynx, and the liquid is particularly difficult to pass through the pharynx, accompanied by nasal reflux, choking cough, etc
.
This is associated with dysfunction of the pharynx, hypopharynx, upper esophageal sphincter (UES), and esophageal rhabdom, making oropharyngeal dysphagia a manifestation of
neurological or muscular disease.
Multiple sclerosis, scleroderma, hyper- or hypothyroidism can cause dysfunction of the pharynx, hypopharynx and UES
.
The lesions of the rhabdomyosis muscle (such as dermatomyositis, polymyositis, muscle atrophy, etc.
) can affect the pharyngeal muscle and esophageal striated muscle, weakening the contraction of the pharyngeal muscle, reducing the pressure of UES and the amplitude of proximal esophageal contraction, all of which can cause oropharyngeal dysphagia
.
In younger patients, oropharyngeal dysphagia is often caused
by muscle disease, esophageal webbing, or oesophageal ring.
In older patients, it is often caused by central nervous system disorders, including stroke, Parkinson's disease, and dementia
.
2.
Esophageal dysphagia
It refers to the obstruction of the esophagus through the esophagus, which can be divided into two categories
: mechanical and dynamic.
(1) Mechanical: When swallowing large pieces or other solid foods, there is no difficulty
in swallowing drinks.
Esophageal tumors, benign strictures, enlarged mediastinal lymph nodes, or congenital aortic arch malformations can cause dysphagia, and sometimes esophageal cancer has not yet obstructed the esophagus, but has invaded the myometrial ganglion cells, causing dysmotilous dysphagia
.
(2) Dynamic: dysphagia is not divided into liquid and solid, mainly seen in achalasia, diffuse esophageal spasm, etc.
, sometimes hysteria
.
Oropharyngeal or esophageal, mechanical or motil,
is first determined.
If it is mechanical dysphagia, it is judged to be benign or malignant and its specific positioning; If dynamic dysphagia is present, the distinction should be made between neuropathic or myogenic pathology, peripheral or central neuropathy, or metabolic or immune disorders
.
Commonly used inspection methods are:
Transnasoesophagoscopy
Auscultation of the neck
Blood tests: including thyroid-stimulating hormone, vitamin B12, and creatine kinase; May be useful, especially in neurogenic dysphagia
Imaging tests: X-rays, computed tomography (CT), magnetic resonance imaging (MRI), chest x-rays, etc
Endoscopy: in oesophageal dysphagia, endoscopy can identify inflammation or cancerous strictures, and if necessary, endoscopic ultrasound or esophageal mediastinal CT scan to determine that lesions are submucous or extraoesophageal and to understand the depth of lesion invaded
Esophageal pH monitoring: criteria for diagnosing reflux disease
Esophageal manometry: indicated for dynamic dysphagia
Pulmonary function tests
References:
1.
World Gastroenterology Organisation Global Guidelines Dysphagia-Global Guidelines and Cascades Update September 2014[J].
Journal of Clinical Gastroenterology, 2015.
2.
WAN Xuehong, LU Xuefeng.
Diagnostics(9th edition)[M].
Beijing:People's Medical Publishing House,2018:27-28.
3.
WANG Wenjing, SUN Huinan, CHEN Xuxin, et al.
Research progress on pathogenesis and treatment of dysphagia[J].
Journal of Translational Medicine,2015(6):377-381
4.
Nam-Jong Paik.
Dysphagia.
Medscape.
5.
ZHU Yueyong,ZHUANG Zehao,DONG Jing.
Gastroenterologist's Handbook of Ward Rounds (2nd Edition)[M].
Beijing:Chemical Industry Press,2017,14-15.
.