DCR: Statin therapy associated with reduced 90-day postoperative mortality after colon cancer surgery

With the advancement of surgical techniques and the optimization of perioperative care in patients undergoing major abdominal surgery, most patients have significantly reduced postoperative adverse outcomes
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Despite these advances, serious non-surgical complications remain high, accounting for approximately 10% of all surgical cases

With the advancement of surgical techniques and the optimization of perioperative care in patients undergoing major abdominal surgery, most patients have significantly reduced postoperative adverse outcomes

 

We performed a retrospective analysis of prospective data on patients from the Swedish Colorectal Cancer Registry
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All adult patients who underwent elective surgery for colon cancer between January 2007 and September 2016 were included in the study

Colorectal Cancer Statistics

 

The results showed that a total of 22,337 patients underwent elective surgery for colon cancer during the study period, of which 6,494 (29%) were classified as statin users
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Despite older age, a higher burden of comorbidities, and less amenable to surgery, statin users showed significant survival benefits

Figure: Statin therapy and risk factors for 90-day postoperative mortality after colon cancer surgery

 

This study demonstrated a significant postoperative benefit for statin users in short-term mortality after elective colon cancer surgery; however, further research is needed to determine whether this relationship is causal
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This study demonstrated a significant postoperative benefit for statin users in short-term mortality after elective colon cancer surgery; however, further research is needed to determine whether this relationship is causal
.

Original source:

Pourlotfi.

Statin Therapy Is Associated With Decresed 90-Day Postoperative Mortality After Colon Cancer Surgery.
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