-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
In the eyes of people who are full of food attributes such as singular cakes and value health, the most terrifying disease is probably diabetes.
Once diagnosed, you must follow the diet plan and various taboos, and you must take hypoglycemic drugs or insulin regularly every day.
.
.
If you think about this, the usual exercise and healthy eating will be more motivational.
After all, Singularity Cake does not want to become a Chinese.
A member of 100 million "sugar friends".
An analysis recently published by Chinese scholars in the journal Diabetes Care shows that the earlier you develop type 2 diabetes, the greater the threat to your health.
The analysis is based on the well-known cardiovascular cohort study in my country-the Kailuan study of 10,700 patients with type 2 diabetes, compared with the data of healthy controls: if the patient is diagnosed with type 2 diabetes before the age of 45, then the follow-up period is all due to The risk of death is 4.
79 times that of the control population, and the risk of cardiovascular disease is also as high as 3.
21 times [1]! In the eyes of many readers, chronic diseases such as type 2 diabetes, hypertension, and heart disease are only available to the elderly, and they are still far away from themselves.
However, a national survey conducted in 2015-2017 showed that 6.
3% of the 30-39-year-old population meets the conditions for diagnosis of diabetes, and the pre-diabetic population accounts for nearly 30% [2].
The rapid rejuvenation of diabetes has reached an alarming level, which is obviously inseparable from the increasingly unhealthy life>
Sitting for a long time without exercising, drinking a large cup of milk tea, eating intemperately, just list a few items, I guess you will get a lot of shots, right? Diagnosing type 2 diabetes early will not only affect blood sugar indicators, but all tissues and organs of the body will be affected, especially the cardiovascular system, which has to bear the burden that it should not bear.
In theory, the longer you have diabetes, the more damage caused by diabetes, and the more serious the consequences [3].
A recent meta-analysis has shown that every increase in age of diabetic patients by one year at the time of diagnosis is related to a 4% reduction in the risk of all-cause death and a 5% reduction in the risk of cardiovascular disease [4], but this does not mean that diabetes is diagnosed in old age.
It will be safer, but if you are diagnosed at a young age, the length of illness and disease burden will be greater, and the cumulative risk will be higher.
Only the patient knows the taste of a true diagnosis of diabetes (picture source: Pixabay).
The analysis of the Kailuan research data by Chinese scholars this time is to follow up patients with type 2 diabetes from the beginning of the diagnosis, and use a case-control study.
Contrast with healthy people with similar conditions.
Among the more than 170,000 participants in the Kailuan study, 101,000 met the screening criteria and were included in this analysis by the research team.
During the average follow-up period of 5.
5 years, there were 11,300 new cases of diabetes among these 101,000 people.
Even considering that the participants are working and retired employees of coal mining groups, most of them are relatively high-risk middle-aged and elderly men.
This incidence rate It is indeed quite high.
After further screening, the research team formed 10,700 newly diagnosed patients into a case-control ratio of 1:1, and analyzed 907 cardiovascular events (725 strokes) and 887 deaths due to various causes during the follow-up period.
The relationship with the age at diagnosis of diabetes.
The results of the analysis can be summarized in the following figure.
Type 2 diabetes is diagnosed before the age of 45.
All-cause death and cardiovascular risk increase are relatively the largest.
As the age of diagnosis increases, the increase in risk gradually decreases, but just like the previous one What has been said, this cannot be interpreted as "the risk of diagnosed diabetes is lower in the elderly".
From the perspective of the disease mechanism, the islet function of patients diagnosed with type 2 diabetes earlier may decline faster, leading to early abnormalities in blood lipids, blood pressure and other indicators, accelerating the occurrence and development of cardiovascular disease.
The heart of this study Vascular diseases are limited to stroke and myocardial infarction, and there are studies that show a similar trend in heart failure [5].
Patients diagnosed earlier may also have more risk factors, such as unhealthy life>
Moreover, studies have shown that young patients are not as self-disciplined as the elderly after diagnosis, and they are more likely to not take medicines on time and do not follow the diet plan [7], so they can't control sugar, and it's strange that they don't come to the door for various risks.
Two days ago, Singularity Cake also saw an analysis, saying that the earlier the diagnosis of diabetes, the greater the risk of dementia[8].
This is even more unbearable to become stupid than taboo.
If you want to keep diabetes far away, you have to work harder, but don't make any confusing remarks that "diabetes does not exist if I am not diagnosed".
.
.
References: 1.
Zhao M, Song L, Sun L, et al.
Associations of Type 2 Diabetes Onset Age With Cardiovascular Disease and Mortality: The Kailuan Study[J].
Diabetes Care, 2021.
2.
Li Y, Teng D, Shi X, et al.
Prevalence of diabetes recorded in China using 2018 diagnostic criteria from the American Diabetes Association: national cross sectional study[J].
BMJ, 2020, 369.
3.
Huo L, Magliano DJ, Rancière F, et al.
Impact of age at diagnosis and duration of type 2 diabetes on mortality in Australia 1997–2011[ J].
Diabetologia, 2018, 61(5): 1055-1063.
4.
Nanayakkara N, Curtis AJ, Stephane H, et al.
Impact of age at type 2 diabetes mellitus diagnosis on mortality and vascular complications: systematic review and meta-analyses[ J].
Diabetologia, 2021, 64(2): 275-287.
5.
Sattar N, Rawshani A, Franzén S, et al.
Age at diagnosis of type 2 diabetes mellitus and associations with cardiovascular and mortality risks: findings from the Swedish National Diabetes Registry[J].
Circulation, 2019, 139(19): 2228-2237.
6.
Steinarsson AO, Rawshani A, Gudbjörnsdottir S, et al.
Short-term progression of cardiometabolic risk factors in relation to age at type 2 diabetes diagnosis: a longitudinal observational study of 100,606 individuals from the Swedish National Diabetes Register[J].
Diabetologia, 2018, 61(3): 599-606.
7.
Nanayakkara N, Pease AJ, Ranasinha S, et al.
Younger people with Type 2 diabetes have poorer self-care practices compared with older people: results from the Australian National Diabetes Audit[J].
Diabetic Medicine, 2018, 35(8): 1087-1095.
8.
Barbiellini Amidei C, Fayosse A, Dumurgier J, et al.
Association Between Age at Diabetes Onset and Subsequent Risk of Dementia[J].
JAMA, 2021, 325(16): 1640-1649.
Source of head picture: Pixabay Author of this article | Tan Shuo
Once diagnosed, you must follow the diet plan and various taboos, and you must take hypoglycemic drugs or insulin regularly every day.
.
.
If you think about this, the usual exercise and healthy eating will be more motivational.
After all, Singularity Cake does not want to become a Chinese.
A member of 100 million "sugar friends".
An analysis recently published by Chinese scholars in the journal Diabetes Care shows that the earlier you develop type 2 diabetes, the greater the threat to your health.
The analysis is based on the well-known cardiovascular cohort study in my country-the Kailuan study of 10,700 patients with type 2 diabetes, compared with the data of healthy controls: if the patient is diagnosed with type 2 diabetes before the age of 45, then the follow-up period is all due to The risk of death is 4.
79 times that of the control population, and the risk of cardiovascular disease is also as high as 3.
21 times [1]! In the eyes of many readers, chronic diseases such as type 2 diabetes, hypertension, and heart disease are only available to the elderly, and they are still far away from themselves.
However, a national survey conducted in 2015-2017 showed that 6.
3% of the 30-39-year-old population meets the conditions for diagnosis of diabetes, and the pre-diabetic population accounts for nearly 30% [2].
The rapid rejuvenation of diabetes has reached an alarming level, which is obviously inseparable from the increasingly unhealthy life>
Sitting for a long time without exercising, drinking a large cup of milk tea, eating intemperately, just list a few items, I guess you will get a lot of shots, right? Diagnosing type 2 diabetes early will not only affect blood sugar indicators, but all tissues and organs of the body will be affected, especially the cardiovascular system, which has to bear the burden that it should not bear.
In theory, the longer you have diabetes, the more damage caused by diabetes, and the more serious the consequences [3].
A recent meta-analysis has shown that every increase in age of diabetic patients by one year at the time of diagnosis is related to a 4% reduction in the risk of all-cause death and a 5% reduction in the risk of cardiovascular disease [4], but this does not mean that diabetes is diagnosed in old age.
It will be safer, but if you are diagnosed at a young age, the length of illness and disease burden will be greater, and the cumulative risk will be higher.
Only the patient knows the taste of a true diagnosis of diabetes (picture source: Pixabay).
The analysis of the Kailuan research data by Chinese scholars this time is to follow up patients with type 2 diabetes from the beginning of the diagnosis, and use a case-control study.
Contrast with healthy people with similar conditions.
Among the more than 170,000 participants in the Kailuan study, 101,000 met the screening criteria and were included in this analysis by the research team.
During the average follow-up period of 5.
5 years, there were 11,300 new cases of diabetes among these 101,000 people.
Even considering that the participants are working and retired employees of coal mining groups, most of them are relatively high-risk middle-aged and elderly men.
This incidence rate It is indeed quite high.
After further screening, the research team formed 10,700 newly diagnosed patients into a case-control ratio of 1:1, and analyzed 907 cardiovascular events (725 strokes) and 887 deaths due to various causes during the follow-up period.
The relationship with the age at diagnosis of diabetes.
The results of the analysis can be summarized in the following figure.
Type 2 diabetes is diagnosed before the age of 45.
All-cause death and cardiovascular risk increase are relatively the largest.
As the age of diagnosis increases, the increase in risk gradually decreases, but just like the previous one What has been said, this cannot be interpreted as "the risk of diagnosed diabetes is lower in the elderly".
From the perspective of the disease mechanism, the islet function of patients diagnosed with type 2 diabetes earlier may decline faster, leading to early abnormalities in blood lipids, blood pressure and other indicators, accelerating the occurrence and development of cardiovascular disease.
The heart of this study Vascular diseases are limited to stroke and myocardial infarction, and there are studies that show a similar trend in heart failure [5].
Patients diagnosed earlier may also have more risk factors, such as unhealthy life>
Moreover, studies have shown that young patients are not as self-disciplined as the elderly after diagnosis, and they are more likely to not take medicines on time and do not follow the diet plan [7], so they can't control sugar, and it's strange that they don't come to the door for various risks.
Two days ago, Singularity Cake also saw an analysis, saying that the earlier the diagnosis of diabetes, the greater the risk of dementia[8].
This is even more unbearable to become stupid than taboo.
If you want to keep diabetes far away, you have to work harder, but don't make any confusing remarks that "diabetes does not exist if I am not diagnosed".
.
.
References: 1.
Zhao M, Song L, Sun L, et al.
Associations of Type 2 Diabetes Onset Age With Cardiovascular Disease and Mortality: The Kailuan Study[J].
Diabetes Care, 2021.
2.
Li Y, Teng D, Shi X, et al.
Prevalence of diabetes recorded in China using 2018 diagnostic criteria from the American Diabetes Association: national cross sectional study[J].
BMJ, 2020, 369.
3.
Huo L, Magliano DJ, Rancière F, et al.
Impact of age at diagnosis and duration of type 2 diabetes on mortality in Australia 1997–2011[ J].
Diabetologia, 2018, 61(5): 1055-1063.
4.
Nanayakkara N, Curtis AJ, Stephane H, et al.
Impact of age at type 2 diabetes mellitus diagnosis on mortality and vascular complications: systematic review and meta-analyses[ J].
Diabetologia, 2021, 64(2): 275-287.
5.
Sattar N, Rawshani A, Franzén S, et al.
Age at diagnosis of type 2 diabetes mellitus and associations with cardiovascular and mortality risks: findings from the Swedish National Diabetes Registry[J].
Circulation, 2019, 139(19): 2228-2237.
6.
Steinarsson AO, Rawshani A, Gudbjörnsdottir S, et al.
Short-term progression of cardiometabolic risk factors in relation to age at type 2 diabetes diagnosis: a longitudinal observational study of 100,606 individuals from the Swedish National Diabetes Register[J].
Diabetologia, 2018, 61(3): 599-606.
7.
Nanayakkara N, Pease AJ, Ranasinha S, et al.
Younger people with Type 2 diabetes have poorer self-care practices compared with older people: results from the Australian National Diabetes Audit[J].
Diabetic Medicine, 2018, 35(8): 1087-1095.
8.
Barbiellini Amidei C, Fayosse A, Dumurgier J, et al.
Association Between Age at Diabetes Onset and Subsequent Risk of Dementia[J].
JAMA, 2021, 325(16): 1640-1649.
Source of head picture: Pixabay Author of this article | Tan Shuo
