Diabetes Care: Over 20 years of research to explore the impact of metformin and lifestyle interventions on the mortality of diabetic patients, the results were shocking!

Suffering from diabetes adult heart's blood vessels , cancer and all-cause mortality rate is higher
.

Although metformin and life>

Diabetic Vascular Metformin This study aims to determine whether metformin or life>

From 1996 to 1999, 3234 high-risk adults with type 2 diabetes were randomly assigned to the intensive life>
.

The placebo and life>but the metformin study continued in the initially randomized patients

But continue the metformin study in the initially randomized patients

It can be seen that in an average of 21 years (interquartile range 20-21 years), 453 participants died
.

Cancer is the leading cause of death (n = 170), followed by cardiovascular disease (n = 131)

Cancer is the leading cause of death (n = 170), followed by cardiovascular disease (n = 131)

Kaplan-Meier survival curve of metformin, life>

Kaplan-Meier survival curve of metformin, life>

Compared with placebo, the ratio and risk of all-cause mortality and specific cause mortality related to metformin and life>

Compared with placebo, the ratio and risk of all-cause mortality and specific cause mortality related to metformin and life>

Similarly, life>
.

The adjusted analysis of diabetes status and duration, BMI, cumulative glucose exposure, and cardiovascular risk yielded results similar to all-cause mortality

The adjusted analysis of diabetes status and duration, BMI, cumulative glucose exposure, and cardiovascular risk yielded results similar to all-cause mortality

All in all, cancer is the main cause of death among people at high risk of type 2 diabetes

DOI: 10.
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