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Diabetes Care: What is the relationship between metformin, vitamin B12 and all-cause mortality in diabetic patients?

 Last Update: 2022-04-17
 Source: Internet
 Author: User

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natural cure type 2 diabetes

vitamin b12 ingredients

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The prevalence of diabetes worldwide has quadrupled over the past few decades, with type 2 diabetes accounting for 90%

Clinical studies have found that the prevalence of vitamin B12 deficiency is significantly increased in diabetic patients, especially those taking metformin

The study included 3277 adults with type 2 diabetes from the National Health and Nutrition Examination Survey (NHANES) and were followed through December 31, 2015

Results showed that 865 all-cause deaths occurred during a median follow-up of 7.

Association of all-cause mortality with reduced sensitivity to cobalamin (vitamin B12) in diabetic patients

The relationship between all-cause mortality and decreased sensitivity to cobalamin (vitamin B12) in patients with diabetes B12) Relationship with reduced sensitivity

Cobalamin sensitivity was assessed by the combination of binary B12low/high and MMAlow/high

In simple terms, serum and dietary vitamin B12 were not associated with reduced mortality

References: Shanjie Wang, Ye Wang, Xin Wan, Junchen Guo, Yiying Zhang, Maoyi Tian, Shaohong Fang, Bo Yu; Cobalamin Intake and Related Biomarkers: Examining Associations With Mortality Risk Among Adults With Type 2 Diabetes in NHANES.
Diabetes Care1 February 2022; 45 (2): 276–284.
https://doi.
org/10.
2337/dc21-1674 References: Shanjie Wang, Ye Wang, Xin Wan, Junchen Guo, Yiying Zhang, Maoyi Tian, Shaohong Fang, Bo Yu; Cobalamin Intake and Related Biomarkers: Examining Associations With Mortality Risk Among Adults With Type 2 Diabetes in NHANES.
Diabetes Care 1 February 2022; 45 (2): 276–284.
https://doi.
org/10.
2337/dc21-1674Shanjie Wang, Ye Wang, Xin Wan, Junchen Guo, Yiying Zhang, Maoyi Tian, Shaohong Fang, Bo Yu; Cobalamin Intake and Related Biomarkers: Examining Associations With Mortality Risk Among Adults With Type 2 Diabetes in NHANES.
Diabetes Care Diabetes Care 1 February 2022; 45 (2): 276–284.
https://doi.
org/10.
2337/dc21-1674

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