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The goal of this work is to determine weight patterns and how blood sugar, blood pressure, and lipids change with age, gender, and race in diabetes diagnosis.
Based on uk clinical practice data, the researchers identified people with type 2 diabetes diagnosed in 1998-2015 (n s 187,601) and compared their weight, glycation hemoglobin, blood pressure and lipid levels with non-diabetic patients of similar age (n s 906,182) by sex and race.
results show that the younger the diagnosis, the greater the corrected average weight difference (95% CI) between people with type 2 diabetes and non-type 2 diabetes: 18.7 (18.3, 19.1) kg at age 20-39 and 5.3 (5.0,5.5) kg at age 80.
white women had the greatest difference in weight, about twice as much as South Asians and blacks.
Although the absolute value is low, the younger the onset of diabetes, the greater the difference in blood pressure: 7 (6,7) mmHg at age 20-39 and -0.5 (-0.9, -0.2) mmHg at age 80.
blood pressure differences were greatest among whites, especially women.
difference in triamglyceride levels was greatest among young men.
, glycation hemoglobin levels were also higher among younger diabetics, especially blacks.
when diagnosed with type 2 diabetes, the difference in weight and blood pressure between young people and older people, women and men, whites and South Asians and blacks was greater than those without diabetes.
these differences were observed, although South Asians and blacks tended to develop diabetes 10 years earlier, or similar or more severe blood sugar abnormalities.
these significant patterns may have an impact on management and prevention.
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