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Dig Dis Sci: Analysis of the recurrence rate of incurable Thyrobacter pyridobacteria and cytomexual viruses in patients with ulcerative colitis who undergoes intestinal tube matching surgery

 Last Update: 2021-01-22
 Source: Internet
 Author: User

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Ulcerative colitis (UC) is an inflammatory bowel disease that has reduced UC's surgical rate to about 25%, but a large number of patients still need surgical intervention.
The general surgical method of UC is intestinal tube matching (IPAA), and UC patients have a higher overall risk of opportitic infections such as Cytobacteria infection (CDI) and cytovirus (CMV) after surgery than patients without inflammatory bowel disease, or even patients with Crohn's disease.
CDI and CMV infection rates and their effects on surgical outcomes and final bag function remain controversial.
, the main purpose of the study was to assess the rate of CDI and CMV recurrence in patients undergoing UC surgery.
secondary purpose is to determine whether antibiotic precautions can prevent CDI or CMV recurrence in patients with a history of CDI or CMV infection undergoing UC surgery.
the study, the researchers collected surgical and clinical data from all UC patients who received IPAA at two medical centers between 2001 and 2017.
observations were the history of Ocythrobacteria or CMV colitis in UC patients prior to surgery and the recurrence of IPAA after surgery.
study included 633 UC patients who received IPAA, 8.1 percent of whom had Thyrobacter difficile and 2.7 percent had CMV infection.
9.8 percent of all people with Ococcal difficile and 5.9 percent of CMV patients relapsed after IPAA.
rates of abdominal sepsis (14.7% vs. 12.7%), 90-day mortality (0%vs. 0.4%), bagitis (36.8% vs.45.0%) or oral rate (7.4% vs.5.4%) did not differ between patients with or without infection.
this study confirms that the infection rate of Thyrobacteria and CMV remains high among UC patients undergoing IPAA surgery, with a significant number of people repeatedly infected during subsequent surgical procedures.
antibiotic prevention in patients with a history of Thyrobacteria disease can reduce the rate of relapse infection.

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