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Inflammatory bowel disease (IBD) is a chronic immuno-mediated disease that is unpredictable and affects about 1.6 million people in the United States.
studies have shown that IBD's disease activity is closely related to sleep and daily rest-activity rhythms (RARs).
is a multi-dimensional biological behavior regulated by its own steady state and circadian rhythm.
IBD rates have increased significantly among people with sleep disorders, with only 10 percent of IBD adults reporting that they sleep well.
RAR is a pattern of 24-hour exercise activity measured by activity recorders that occur during sleep and sleep, and reflects the effects of endoendemic circadian rhythms and exo-effects such as light, physical activity, and other environmental cues.
interference with RAR's experimental operations (light/dark manipulation or forced anachronistic activity) in IBD mouse models can lead to colon inflammation, weight loss, and damage to intestinal tissue.
Therefore, the purpose of this study is (1) to describe the relationship between sleep characteristics and RAR in IBD patients; (2) to compare sleep characteristics, RAR with gastrointestinal (GI) symptoms through disease activity; and (3) to describe the association between sleep characteristics in IBD adults, RAR and GI symptoms.
researchers conducted a cross-sectional study of adult patients with IBD.
measured sleep characteristics and RAR scores, changes in gastrointestinal symptoms (PROMIS-GI), and changes in disease activity.
results showed that 23 (60.6%) of the 37 IBD patients were in the period of disease remission, and that the sleep efficiency of these patients was not related to disease activity.
the daytime stability of the RAR is associated with a stomach reflow burning sensation (r -.491, p s.005) and bloating (r s-.469, p s.008).
, we can see that the RAR in IBD patients may have been destroyed, which is associated with GI symptoms, such as bloating, frequent seizures.
