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    Home > Active Ingredient News > Digestive System Information > Dig Dis Sci: Thiopurine monotherapy is effective in maintaining clinical remission in patients with mild to moderate inflammatory bowel disease

    Dig Dis Sci: Thiopurine monotherapy is effective in maintaining clinical remission in patients with mild to moderate inflammatory bowel disease

    • Last Update: 2022-05-11
    • Source: Internet
    • Author: User
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    Crohn's disease (CD) and ulcerative colitis (UC) are a complex group of inflammatory bowel diseases (IBD) with major symptoms including fistulas, perforations, malnutrition, and intestinal obstruction


    Crohn's disease (CD) and ulcerative colitis (UC) are a complex group of inflammatory bowel diseases (IBD) with major symptoms including fistulas, perforations, malnutrition, and intestinal obstruction


     

    This retrospective study included adults with mild-to-moderate IBD who started thiopurines without biological therapy


     

    Of the 230 CD patients, 64 (72%) had no treatment failure with a mean follow-up of 3.


    Figure: Time chart of patient relapse

     

    This study demonstrates that thiopurine monotherapy is associated with clinical disease maintenance in remission in mild-to-moderate uncomplicated IBD, and that thiopurine monotherapy may represent a lower cost, convenient and effective alternative to biologics


    This study demonstrates that thiopurine monotherapy is associated with clinical disease maintenance in remission in mild-to-moderate uncomplicated IBD, and that thiopurine monotherapy may represent a lower cost, convenient and effective alternative to biologics


    Original source:

    Grant E.


    Grant E.
    Barber.
    Et al.
    Thiopurine Monotherapy Is Effective in Maintenance of Mild-Moderate Inflammatory Bowel Disease.
    Digestive Diseases and Sciences.
    2022.
    Thiopurine Monotherapy Is Effective in Maintenance of Mild-Moderate Inflammatory Bowel Disease.


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