-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
The tonsils are important lymphoid organs with immune function, which is the first line of defense of the immune system against swallowing or inhalation of foreign pathogens, so this lymphatic organ is often congested
Rheumatoid arthritis (RA) is a systemic autoimmune disease
In further in vitro cell experiments, the researchers demonstrated that Salivaricin can specifically inhibit the differentiation and activation of follicular helper T (Tfh) cells, while cells Th1, Th17 and Treg (regulatory T cells) that promote inflammation in the peripheral blood have no significant effect
Recently, in a new study published in Advanced Science, the research group of Professor Li Zhanguo from Peking University People's Hospital and the research group of Wang Jun, a researcher at the Institute of Microbiology of the Chinese Academy of Sciences, cooperated to discover the immunomodulatory effect
Rheumatoid arthritis (RA) is a systemic autoimmune disease
By analyzing the metabolic potential of the tonsil flora, the team previously found flaws
In addition, Salivaricins, produced by Streptococcus salivary, are also an antimicrobial peptide
In the new study, the researchers delved into the immunomodulatory effects
In further in vitro cell experiments, the researchers demonstrated that Salivaricin can specifically inhibit the differentiation and activation of follicular helper T (Tfh) cells, while cells Th1, Th17 and Treg (regulatory T cells) that promote inflammation in the peripheral blood have no significant effect
In conclusion, the study reveals the immunomodulatory role of Salivaricin in autoimmune diseases, demonstrating that it beneficially regulates host immunity
Thesis Link:
https://doi.
