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Serum lipoproteins, such as high-density lipoprotein (HDL), may affect the severity of idiopathic pulmonary fibrosis (IPF)
.
Recently, Eur Respir J, an authoritative journal in the field of respiratory diseases, published a research article in which researchers explored the relationship between serum lipid and lipoprotein levels and clinical outcomes in patients with IPF
.
The researchers found that queue (59 IPF subjects, 56 healthy volunteers) clinical data and serum lipids were analyzed, and used from lung fibrosis fund independent multicenter cohort will register at (207 IPF by Examiner) to verify
.
Researchers used Pearson correlation and multivariate analysis to assess the association between blood lipids and clinical endpoints (forced vital capacity, FVC; 6-minute walk distance, 6MWD; gender and age physiological index, GAP; death or lung transplantation)
The higher S-HDLPNMR level in the serum of IPF patients is negatively correlated with the GAP index and lower mortality or lung transplantation
Original source:
Amisha V.
Barochia,et al.
Serum levels of small HDL particles are negatively correlated with death or lung transplantation in an observational study of idiopathic pulmonary fibrosis .
Eur Respir J.
2021.
https://erj.
ersjournals.
com/content/early /2021/04/19/13993003.
04053-2020Serum levels of small HDL particles are negatively correlated with death or lung transplantation in an observational study of idiopathic pulmonary fibrosis in this message
