"False heart failure"? 81-year-old grandmother "engine" failed, the original blood has this disease!

Heart, is the human body's "engine" once the problem, will endanger life caused by the "engine" failure of many reasons are the engine itself problems and some may be "external force" stuck in the "engine" 81-year-old Hangzhou grandma (aka) inside the body of the "engine" on the problem, however, she turned to a number of hospitals but never found the real cause of the "engine failure" look at the situation More and more critical grandma came to Zhejiang University Medical College affiliated with the first hospital Jiang Hospital District in the face of grandma's "weird disease" experts to peel off the fog shrouded in grandma's body, grandma suffered from a blood disease caused her heart muscle to appear some things to destroy its normal operation of the treatment of grandma's "life engine" began to run well again! The 81-year-old grandmother suffered a "strange illness" "Thank you doctor."
" October 14, Grandma Sun, accompanied by her son Mr. Li (analyte), came to jiang hospital area of Zhejiang University Hospital and walked into the specialist outpatient review of Dr. Yan Hui, director of cardiovascular medicine.
examination, Grandma Sun recovered well, although the legs and feet are not particularly convenient, but her face is ruddy, good spirit, heart indicators have also improved.
time to go back a year, when Dr. Yan Hui first met her grandmother, her condition was very bad - she was weak, her lower limbs were puffy, her chest was tight.
Grandma is Hangzhou Jiande people, has been a year of her, the body has been called strong, a pair of children are also family harmony, she helped to pick up and drop off grandchildren, children also often take her to travel together, enjoy the joy of heaven.
However, at the beginning of 2019, Grandma Quickly lost weight, while there were weak legs and feet, the whole body is weak, but at that time the whole family thought that these are the normal performance of old age, there is no special attention, Grandma will still go out with her children to play, but gradually, from once can act together, into Grandma "can not walk, need to sit and rest."
In May 2019, Grandma Sun appeared again the symptoms of swelling of the lower extremities, this time, son Mr. Li anxious, hastened to take her to the local hospital for medical treatment, at this time Grandma's "strange disease" has begun to appear, she suffers from high blood pressure all year, and at this time has become low blood pressure.
the local hospital did not look into the reasons for the change, only to treat Grandma's puffiness.
after treatment, Grandma's condition improved, but half a month later, Grandma's legs and feet swelled up again, but also increased the symptoms of chest tightness.
To a number of hospitals, after a series of examinations, Grandma's blood indicators of nitrate peptide prebiosis is greater than 9000pg/ml (this is one of the most important indicators of heart failure, the normal value is generally below 125pg/ml), while the serum tsyri calcitonin indicators are also high, was diagnosed as heart failure.
, after further examination of heart B super, coronary vascular giore, etc., the local hospital did not find that Grandma Sun has blood vessel stenosis and other common problems leading to heart failure.
is the cause of Grandma's "heart failure"? The diagnosis got lost and the treatment became difficult.
grandmother's illness is getting more and more serious, all day can only lie in bed, weak, and even fainted twice.
anxious Mr. Li asked around, with his already very weak grandmother rushed to the Jiang Hospital District of Zhejiang University Hospital, into the cardiovascular medicine director of the specialist clinic.
the wire peeling finally dialed the clouds to see the day" we ran a lot of hospitals, how can not find the cause.
", Mr. Li can't wait to come up with his grandmother's checklist.
Yan Hui director of the doctor carefully looked at Grandma's examination list, keenly found a detail: from Grandma's heart super-examination results, you can see that her heart muscle is diffuse thickening, left heart chamber is small, heart muscle echo is sand-like, but her electrocardigraph is low voltage change.
generally speaking, if the heart muscle thickens, the electrocardial chart shows a high voltage change, while she is an abnormally low voltage change.
" Grandma's heart super shows that the heart muscle is very thick, but the electrocardiological map is a low voltage change with rich experience in the diagnosis of heart disease, Dr. Yan Hui immediately associated with a disease that causes this abnormal phenomenon - myocardial amyloid degeneration.
So, she immediately arranged for grandma related blood tests, bone marrow punctures, abdominal wall adipose tissue biopsy, the results soon came out - Grandma Sun suffered from a blood disease called "systemic light chain amyloid degeneration", resulting in myocardial amyloid degeneration, which eventually led to heart failure.
" patient's pathogenesis is in the heart, but the root cause is in the blood.
, " said Dr. Yan Hui, "so it will always be difficult to find the cause."
"" systemic amyloid degeneration is a blood disease, the cause of the disease is more complex, simply put, is the malignant proliferation of blood cells, secreting a large number of abnormal proteins, these abnormal proteins in the form of amyloid fibers deposited in the human body organs and cells, so that the affected organ function gradually exhausted a clinical syndrome.
"Systemic amyloid degeneration is different due to deposited amyloid proteins and affected organs, so clinical manifestations vary, with liver, kidneys, nerves, heart, gastrointestinal tract, etc. commonly affected organs, and affected tissues such as skin, tongue and lymph nodes," said Professor Cai Zhen, deputy director of the bone marrow transplant center and director of the Multiple Myeloma Treatment Center of Zhejiang University.
" systemic amyloid degeneration can be divided into several types, grandma suffered from systemic light-chain amyloid degeneration is one of the most common types.
" amyloid protein deposited between her heart muscle fibers, causing her atrium to enlarge, the chamber and valve to thicken, eventually leading to heart failure.
, " said Dr. Yan Hui.
Find the cause, you can also treat the disease, Zhejiang University Hospital Cardiovascular Medicine and bone marrow transplant center multi-expert team jointly tailored treatment plan for Grandma Sun, now, Grandma's heart indicators are improved, and returned to normal life.
the disease is highly susceptible to misdiagnosis" This year, we have treated a number of patients with similar diseases.
"In recent years, with economic and social development, lifestyle changes and social aging, the incidence of the disease has been increasing year by year, " said Dr. Guo Xiaogang, director of cardiovascular medicine at Zhejiang University Hospital.
" Director Guo Xiaogang said, because myocardial amyloid degeneration in the clinical performance of the lack of specificity, so lead to early diagnosis difficulties, easy to misdiagnose, patients mainly clinical manifestations of shortness of activity, limb edema, abdominal water, fainting, etc. , is often considered to be left myocardial hypertrophy of other diseases, such as hypertrophy cardiomyopathy, hypertensive heart disease, aortic stenosis, resulting in patients delayed illness, poor prognosis.
patients with heart failure combine to have the following characteristics, it is necessary to consider that the cause may be myocardial amyloid degeneration: 1 large adcardia, small avical cavity, uniform thickening of the heart muscle, accompanied by aggressive and incurable heart failure 2 left heart chamber hypertrophosis Accompaniment electrocardiogram low voltage 3 used to have high blood pressure, but now there is a carried low blood pressure 4 tongues wide fat thick with tooth marks, dark circles "cardiomyopathy amyloid degeneration is a rapid progression of the disease, if not diagnosed and treated in a timely manner, the survival period is very short.
" Zhejiang University Hospital experts remind that if the patient suffers from heart failure, at the same time have the above symptoms, it is recommended to carry out early myocardial amyloid degeneration examination, early detection of the disease, and as soon as possible to start the treatment of the original disease, help to improve the prognosis.
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