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    Home > Active Ingredient News > Digestive System Information > Front Oncol: Radiofrequency ablation (RFA) after neoadjuvant chemotherapy (NAC) improves the prognosis of ablative colorectal cancer liver metastases (CRLM) patients

    Front Oncol: Radiofrequency ablation (RFA) after neoadjuvant chemotherapy (NAC) improves the prognosis of ablative colorectal cancer liver metastases (CRLM) patients

    • Last Update: 2021-11-11
    • Source: Internet
    • Author: User
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    Radiofrequency ablation (RFA) plays a vital role in patients with unresectable colorectal cancer liver metastases (CRLM)


    Radiofrequency ablation (RFA) plays a vital role in patients with unresectable colorectal cancer liver metastases (CRLM)


    The study mainly retrospectively included CRLM patients recorded by Zhejiang Cancer Hospital from January 2009 to June 2020, and were divided into two groups according to the presence or absence of NAC


    The study mainly retrospectively included CRLM patients recorded by Zhejiang Cancer Hospital from January 2009 to June 2020, and were divided into two groups according to the presence or absence of NAC


    From 2009 to 2020, a total of 149 CRLM patients met the inclusion criteria: 88 cases were in the RFA group alone, and 61 cases were in the RFA+NAC group


    The incidence of postoperative complications in the NAC group was higher than that in the RFA group (16.



    complication

    The median follow-up time for all patients was 30.


    The median follow-up time for all patients was 30.



    3-year LTPFS rate before and after PSM





    Multivariate analysis showed that the use of NAC was LTPFS (HR, 0.


    In summary, studies have shown that for ablated CRLM patients, the prognosis of RFA + NAC is better than RFA alone


    In summary, studies have shown that for ablated CRLM patients, the prognosis of RFA + NAC is better than RFA alone
    .
    According to the current research results, the application of NAC before RFA may become the standard treatment
    .
    Studies have shown that for patients with ablative CRLM, the prognosis of RFA + NAC is better than RFA alone
    .
    According to the current research results, the application of NAC before RFA may become the standard treatment
    .
    Studies have shown that for patients with ablative CRLM, the prognosis of RFA + NAC is better than RFA alone
    .
    According to the results of current research, the application of NAC before RFA may become the standard treatment
    .

    Original source:

    Original source:

    Chen Y, Xu Y, Xu L, Han F, Huang Y, Jiang H, Wu J and Zhang Y (2021) Neoadjuvant Chemotherapy Followed by Radiofrequency Ablation Prolongs Survival for Ablatable Colorectal Liver Metastasis: A Propensity Score Matching Comparative Study.
    Front.
    Oncol .
    11:758552.
    doi: 10.
    3389/fonc.
    2021.
    758552

    Chen Y, Xu Y, Xu L, Han F, Huang Y, Jiang H, Wu J and Zhang Y (2021) Neoadjuvant Chemotherapy Followed by Radiofrequency Ablation Prolongs Survival for Ablatable Colorectal Liver Metastasis: A Propensity Score Matching Comparative Study.
    Front.
    Oncol .
    11:758552.
    doi: 10.
    3389/fonc.
    2021.
    758552

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