Gut: Dietary fiber and IBS: How to transform functional characteristics into clinical value in the era of personalized medicine?

Dietary fiber includes a wide range of indigestible carbohydrates found in plant foods , and is defined by the Food Code as indigestible carbohydrates composed of at least three monomers
.

For clinicians, understanding the functional characteristics of individual fibers and the subsequent physiological responses can guide clinical decision-making, and on this basis, they can manipulate their intake to obtain specific clinical benefits

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Currently, clinical guidelines for the use of fiber supplements in patients with IBS provide one-size-fits-all recommendations with limited value
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Recently, researchers reviewed and discussed data and concepts surrounding the functional characteristics of fiber and subsequent physiological responses in patients with IBS, with a view to applying this knowledge to the precise use of fiber supplements

The main findings of the researchers are: First, individual fibers cause highly different physiological responses, which are related to their functional properties rather than solubility
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Second, the current evidence focuses on the use of fiber as a monotherapy for IBS symptoms, without attempting to use these functional properties to induce specific, symptomatic effects, or to use different types of dietary fiber as adjuvant therapy

 

Overview of pure dietary fiber types (and wheat bran) and their overlapping functional properties

An overview of pure dietary fiber types (and wheat bran) and their overlapping functional properties

Therefore, the individualization of fiber therapy can target several treatment goals, including normalizing intestinal habits, regulating the function of the intestinal microbiota, making it healthy, and correcting the microbial effects of other diet therapies
.

From this perspective, expanded fiber with a lower degree of fermentation can provide the effect of adjusting the intestinal habit index; slow-fermented fiber can enhance the activity of the intestinal microbiota; the combination of two fibers may provide two benefits while optimizing The activity of the microbiota in different areas of the entire colon

Expanded fiber with a low degree of fermentation can provide the effect of regulating the intestinal habit index; slow-fermented fiber can enhance the activity of the intestinal microbiota; the combination of two types of fiber may provide two benefits, while optimizing the microbes in different areas of the entire colon Group activity Expanded fiber with a low degree of fermentation can provide the effect of adjusting the intestinal habit index; slow fermented fiber can enhance the activity of the intestinal microbiota; the combination of two types of fiber may provide two benefits while optimizing the entire colon.

Understand the individual fibers of features and physiological responses consequent understanding of individual fibers and physiological features of the ensuing reaction use a combination of fiber may have the added value of the use of fiber combinations may have a value-added physiological reflect the heterogeneity of IBS patients on the heterogeneity of fiber response in patients with IBS physiological heterogeneity is reflected in the heterogeneity of fiber response to physiological reactions as gastrointestinal symptoms of IBS adjustment strategy will regulate physiological responses as gastrointestinal symptoms of IBS strategy

In short, understanding the response of the digestive tract to specific fibers, especially those related to personal physiology, will be the direction of personalized fiber therapy in the future, which can help strengthen the personalized management of IBS patients
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Original source:

Original source:

Daniel So et al.

Dietary fibres and IBS: translating functional characteristics to clinical value in the era of personalised medicine.

Daniel So et al.

 

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