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Hypertension: Kidney damage in patients with primary aldosteronism

 Last Update: 2021-07-31
 Source: Internet
 Author: User

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As we all know, aldosteronism in patients with chronic kidney disease progressed rapidly, heart vascular complication rate is higher

Heart blood vessels

Recently, a research article was published in Hypertension, the authoritative cardiovascular journal.

The researchers evaluated the subjects with global and segmental glomerulosclerosis, interstitial fibrosis, inflammatory cell infiltration, arteriosclerosis, arteriolar hyaline and mineralocorticoid receptor, 11β-hydroxysteroid dehydrogenase type 1 and 2 And the immunoreactivity of renin was quantitatively evaluated, and additional ultrastructural analysis was performed on 3 patients with hyperaldosteronism

immunity

Typical photos of chemistry and electron microscopy

Researchers found that both mineralocorticoid receptors (P<0.

The above results indicate that patients with hyperaldosteronism have more obvious total kidney damage

Original source:

Hiroko Ogata.

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