Hypertension: The association between polycystic ovary syndrome, obesity, and weight gain and pregnancy hypertension

A population-based prospective cohort study aims to assess the role of polycystic ovary syndrome (PCOS), obesity, weight gain, and asosteroidemia in the development of pregnancy hypertension (HDP) in PCOS and non-PCOS women, according to a recent study published in the journal Hypertension.
the study population were women with HDP (n=408) or non-HDP (n=3373), who received long-term follow-up from the ages of 14 to 46.
confirmed the diagnosis of HDP in participants by combining hospital discharge records, Finnish medical birth registration data and questionnaire data at age 46.
Women with self-reported polycystic ovary syndrome (srPCOS; n=279), defined as 31-year-olds with less admins and more hair, or diagnosed with PCOS at age 46, were compared with women who did not report PCOS (n=1577).
increased risk of HDP in women with srPCOS (ratio of 1.56 (95% CI is 1.03-2.37)), the correlation disappeared after adjusting the BMIs.
the increase in body mass index (BMO) in srPCOS women aged 14 to 46 with HDP was significantly higher than that of women without HDP in srPCOS (medians (median range) of 9.82 (6.23-14.6) and 7.21 (4.16-10.5) kg/m2;P-lt;0.001).
women who are not PCOS, women with HDP (7.54 (5.32-11.62) kg/m2; The increase in body mass index (BMI) was significantly higher than that of women without HDP (6.33 (3.90-9.33) kg/m2; P<0.001)。
increase in waist circumference between the ages of 31 and 46 was associated with HDP and not related to PCOS.
asosteroidemia was not associated with HDP between the ages of 31 and 46 (1.44.
, obesity, especially abdominal obesity, and weight gain between puberty and age 46, rather than srPCOS or asosteroidemia, were associated with an increased risk of HDP.