Instead of PCR, RPA has become a powerful tool for pathogen detection

Biocom reports: Recombinase Polymerase Amplification ( RPA ) is known as a nucleic acid detection technology that can replace PCR (developed by the British company TwistDx Inc )

In a series of articles published this year, RPA technology is widely used in the detection of common pathogenic bacteria such as Mycobacterium tuberculosis, drug-resistant bacteria MRSA , and Salmonella

Application of RPA in the field of clinical diagnosis

Clostridium difficile ( C.

It is estimated that about one-third of the world’s people are latent with tuberculosis ( TB ) pathogens, most of which are dormant in the lungs

The abuse of antibiotics has led to an increase in drug-resistant bacteria, which has now become a global public health problem

A study in " Microchimica Acta " in February this year demonstrated an RPA chip that can simultaneously amplify and detect three pathogens , including Neisseria gonorrhoeae , Salmonella enterica and MRSA

Application of RPA in the field of food safety

The Shiga toxin-producing Escherichia coli STEC is the most serious food-borne pathogen in the world

Salmonella is a major food-borne pathogen

PCR-ELISA is already a mature technology with a wide range of uses

Biological Communication Editor: Ye Yu