it is beyond logic and above reason! New enzymes allow you to switch blood types

What do you do if one of your patients needs a blood transfusion and you don't have his blood type in your blood bank? This is a problem that scientists have been trying to solve for many years but have yet to find an economic solution, which has changed up to now Chemists and scientists at the blood research center at the University of British Columbia in Canada have created an enzyme that may potentially solve the problem The enzyme can modify sugars, commonly known as antigens, that are common in type A and type B blood, making blood more like type o Type O blood is considered as a universal blood donor It can be transfused to patients of any blood type "We have produced a mutant enzyme that can effectively cut off the sugars in type A and type B blood, and is more effective in removing the type of a anti atom that the parent enzyme is difficult to fight against." David Kwan, lead author of the study and a postdoctoral researcher at the school of chemistry, said To create this high-performance enzyme that can effectively cut off sugars, researchers used a new technology called directed evolution, which involves inserting mutations into genes encoding enzymes and selecting variants that can more effectively cut off antigens The efficiency of these enzymes can be increased by 170 times in only five generations Using the enzyme, jayachandran kizhakkedathu, an associate professor at the University of British Columbia, and colleagues at the blood research center realized the removal of most antigens from blood types A and B But before it can be used in clinical trials, the enzyme must be able to remove all antigens The immune system is highly sensitive to blood group, even a little residual antigen can induce immune response "This concept is not new, but we need too many enzymes to achieve this before, which is very impractical." Steven, Professor, Department of chemistry, University of British Columbia? Said Steve withers "Now I am very confident that we have taken a big step forward." The difference between type A, B and O blood lies in the existence of slightly different carbohydrate structures around each type of red blood cell Both type A and type B red blood cells have an extra layer of sugar on their surface (BIOON Com)