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Invasive mycosis (IFD) is a common and potentially life-threatening complication in the haematology-oncology population, with patients receiving remission-induced therapy for acute myeloid leukemia (AML) having a higher
risk of developing invasive mycosis (IFD).
The study was a single-center retrospective study of patients with
bone marrow malignancies who received intensive chemotherapy continuously between 2014 and 2021.
Figure 1.
Figure 2: Overview
of study inclusion.
Figure 3.
Figure 4.
A total of 192 patients with bone marrow malignancies received 300 courses of intensive chemotherapy
.
In summary, diagnostic-driven therapy, without universal aggressive mold prevention, is a viable strategy for IFD therapy and can limit unnecessary antifungal therapy during intensive chemotherapy
.
Original Source:
De Kort EA, Buil JB, Schalekamp S, Schaefer-Prokop C, Verweij PE, Schaap NPM, Blijlevens NMA, Van der Velden WJFM.