J Gastroenterology: Patients with functional dyspepsia experience significant weight loss after gastrointestinal infection

Functional dyspepsia (FD) is a common gastrointestinal (GI) disease that can have a considerable impact on patients' quality of life and impose a significant economic burden on society
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The Rome IV guidelines define FD as a disorder of gastrointestinal origin that affects daily life, such as postprandial fullness, early satiety, epigastric pain, and epigastric burning without an underlying organic disease

Functional dyspepsia (FD) is a common gastrointestinal (GI) disease that can have a considerable impact on patients' quality of life and impose a significant economic burden on society

 

Investigators enrolled consecutive treated FD patients in this study and collected and assessed symptom frequency and severity in patients
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Patients were identified as PDS, EPS, or overlapping groups common to both diseases based on severity scores

statistics

 

In a cohort of 459 FD patients, 36% were characterized as having PDS, 9% had EPS, and 55% had overlap
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PI episodes and positive HP status were reported in 20% and 14% of patients, respectively, with no significant difference between subgroups (p=0.

Figure: Weight loss in different patients

 

This study identified PI episodes of FD symptoms as a risk factor for weight loss in this subset of patients, but not with PDS, EPS, or symptom patterns in overlapping subgroups
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People with HP infection are less likely to experience severe weight loss

This study identified PI episodes of FD symptoms as a risk factor for weight loss in this subset of patients, but not with PDS, EPS, or symptom patterns in overlapping subgroups

 

Original source:

Jolien Schol.

ostinfectious onset in functional dyspepsia is a risk factor for weight loss.
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