J Rheumatol: Comparison of low-field magnetic resonance imaging, ultrasound and clinical outcomes of psoriasis arthritis

Inflammation Control Trials (TICOPA; isrctn.com: ISRCTN30147736) compared standard treatment (StdC) for early psoriasis arthritis (PSA) with strict control (TC) and showed that TC outcomes betterThis sub-study assessed the performance indicators of modern imaging results and compared them with clinical dataassessed non-comparative 0.2T magnetic resonance imaging (MRI; one-handed) using a combined overall inflammation score of the Rheumatology Outcomes (OMERACT) PsA MRI Scoring System (PsAMRIS)These scores are scored and added to ultrasound (US; the same hand) grayscale, power Doppler, and erosion of the palm knuckles (MCP) and near-side knuckles (PIP)78 patients had paired US data (baseline and 48 weeks), 61 patients had paired MRI data, and 50 had matching clinical, MR, and US dataAt MCP levels, there were significant intra-group changes in the inflammatory PsAMRIS components: MRI overall inflammation (median difference (range), standardized response average (SRM): TC and StdC were 3.25 (-5.0 to 12.0), 0.68; 1.0 (-4.5 to 17.5), 0.45The differences in the US group are similar: TC and StdC are 1.0 (-13.0 to 23.0), 0.45; 3.0 (-6.0 to 21.0), 0.77There were no differences between treatment groupsThe study found a significant correlation between baseline and changes in MRI and US scoresThere was a significant correlation between the baseline PsA disease activity score and the overall INFLAMMATION score of MRI (MCP, PIP's Spearman, respectively: 0.46, 0.63)There is no difference in the progress of erosionPsAMRIS and US inflammation scores showed good reactivenessNo intergroup differences were found, but the sub-study may not be sufficient to determine the difference between the two treatment strategies