JCEM: Analysis of the efficacy of somarutide on cystic fibrosis-related diabetes
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Last Update: 2020-06-25
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Source: Internet
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Author: User
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Although there is evidence that poor blood sugar control is associated with poor clinical outcomes in patients, most cystic fibrosis-related diabetes (CFRD) patients have poor blood sugar controlRecently, the authoritative journal Journal of Endocrinology and Metabolic Diseases published a study aimed at clarifying the efficacy of increasing sonmalutide (GLP-1RA) in basic insulin therapy for blood sugar controlsubjects in the study used somarutide weekly instead of fast-acting insulin and continued to use basic insulinThe researchers measured the levels of glycifyding hemoglobin in CFRD patients and monitored their blood sugar continuouslythe 3 months after the addition of sommarnotide treatment, the subjects' blood sugar control improved significantly, with glycifyding hemoglobin decreased from 9.1% to 6.7%, and continuous blood sugar monitoring was a stable sugar reduction pattern (average blood sugar was 142 mg/dL, SD was 51)There was no significant increase in plasma trypsin concentration, it is possible to see that small doses of somarutide can replace insulin in meals, and that combined with basic insulin can control blood sugar in CFRD patients at optimal levels
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