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In Japan, the prevalence of diabetes has increased significantly since World War II due to changes in life>
.
Diabetes has now become a major public health problem and an important risk factor for various diseases and conditions, including cardiovascular disease
.
Childhood cancer survivors who receive high therapeutic doses of radiation have an increased risk of developing diabetes, especially systemic or abdominal cancer
A study published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases, aims to investigate the effect of radiation on the incidence of diabetes in survivors of the atomic bomb (A-bomb), and whether dose-response is affected.
The influence of other factors, including city, gender and age at the time of bombing (ATB)
From 1969 to 2015, researchers observed 9,131 participants without diabetes at baseline through biennial clinical examinations
.
Cox proportional hazards models were used to estimate hazard ratios (HR) to assess the dose-response of diabetes incidence
.
During the study period, researchers identified a total of 1,417 cases of diabetes
.
The overall crude incidence rate was 7.
01 persons/1000 persons/year
Thus, among the atomic bomb survivors, radiation was found to be associated with the incidence of diabetes
.
Results were inconsistent with urban and ATB age, which may suggest a possible confounding factor in the association of radiation with diabetes
.
Among atomic bomb survivors, radiation was found to be associated with incidence of diabetes
Original source:
Original source:Yoshimi Tatsukawa.
et al.
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