JGH: Analysis of the prevalence and risk factors of metabolic-related fatty liver in HIV-infected people in China

Non-alcoholic fatty liver disease (NAFLD), rather than hepatitis C or hepatitis B, is currently the most common liver disease among people living with HIV (PLWH)
.
The characteristic of NAFLD is that in the absence of a high-fat diet, the proportion of fatty degeneration in liver cells is greater than 5%

In this cross-sectional study, transient elastography for liver testing was performed in PLWH without heavy drinking and hepatitis B and C virus infection

Among the 361 PLWH included, the prevalence of NAFLD and MAFLD were 37.
67% and 34.
90%, respectively
.
Compared with the non-MAFLD group, the level of alanine aminotransferase (ALT) in the MAFLD group was increased (44.

Figure: Display of metabolic-related fatty liver risk factors in HIV-infected patients

This study confirmed that one third of HIV-infected patients have MAFLD, which is highly consistent with the prevalence of NAFLD
.
Therefore, clinicians need to conduct routine screening for MAFLD in HIV-infected patients to improve the prognosis of these patients

Original source:

Danping Liu.