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JGH: Immunomodulators with vedolizumab have potential benefit in maintaining ulcerative colitis remission

 Last Update: 2022-02-17
 Source: Internet
 Author: User

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ulcerative colitis pathology

what cell therapy

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Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) with an unpredictable clinical course characterized by intermittent disease relapses

Patients enrolled in this study were from a phase 3 study in Japan, all of whom received vedolizumab for induction and maintenance (300 mg IV)

The results of the study showed that at week 10, the differences in clinical response, clinical remission and mucosal healing rates between the different groups (combination vs single drug use) were 0.

Infect

This study demonstrates that immunomodulators may be beneficial in maintaining the clinical efficacy of vedolizumab, a possibility that may be related to the different modes of action of vedolizumab and IM

Makoto Naganuma.

Potential benefits of immunomodulator use with vedolizumab for maintenance of remission in ulcerative colitis.

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