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OBJECTIVE: There are few prognostic data in patients with gout and COVID-19 .
The study aimed to assess whether gout is a risk factor for diagnosing COVID-19 and COVID-19- related death, and to test for sex- and drug-specific risk differences .
This study aimed to assess whether gout is a risk factor for COVID-19 and COVID-19 diagnosis - related death, and to test for sex- and drug-specific risk differences .
associated risk factors for death, and to test for sex- and drug-specific risk differences .
Methods : The researchers used data from the UK Biobank, which included 15,871 gout patients
.
Using a case-control study design, multivariate adjusted logistic regression was used in the following analyses:Methods : The researchers used data from the UK Biobank, which included 15,871 gout patients .
Using a case-control study design, multivariate adjusted logistic regression was used in the following analyses:
Models 1 and 2 were adjusted for age group, sex, race, Townsend deprivation index, BMI , and smoking status
Results: Results: In the cohort of patients with confirmed COVID-19, gout was associated with a diagnosis of COVID-19 (odds ratio [OR] 1.
The researchers found no significant difference in the risk of death associated with COVID-19 based on urate-lowering therapy or colchicine prescription .
When gout patients were stratified by vaccination status, the risk of a COVID-19 diagnosis was significantly higher in the unvaccinated group (1.
21, 1.
Conclusions: Conclusions: Gout was a risk factor for COVID-19- related death in the UK Biobank cohort, and women with gout had an increased risk driven by risk factors independent of metabolic comorbidities of gout
Source:
Topless, Ruth K et al.
Gout and the risk of COVID-19 diagnosis and death in the UK Biobank: a population-based study.
The Lancet Rheumatology, Volume 4, Issue 4, e274 - e281.
Topless, Ruth K et al.
Gout and the risk of COVID-19 diagnosis and death in the UK Biobank: a population-based study.
The Lancet Rheumatology, Volume 4, Issue 4, e274 - e281.
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