Lancet Sub-Journal | Chinese Scholars: The Influence of Dairy Products Intake on Intestinal Microbes and Heart Health

The human gut microbiota is composed of trillions of microbial cells and thousands of bacterial species.

Among the factors that affect the gut microbiota, diet is a key component.

The composition of the gut microbiota is related to cardiometabolic diseases such as obesity, type 2 diabetes and arteriosclerosis.

Although some studies have shown the influence of dairy products intake on the intestinal microbiota, they are generally cross-sectional or short-term intervention studies, or only focus on a few intestinal bacteria.

So, is the structure or composition of the intestinal microbiota associated with dairy products related to cardiometabolic risk factors? For this reason, life sciences experts from Fudan University and Zhejiang University of assumptions, dairy food intake by regulating intestinal microbial characteristics and associated circulating metabolite may contribute to heart metabolism, relevant results published in " The Lancet " child Published in Ebiomedicine magazine.

Dairy food intake by regulating intestinal microbial characteristics and associated circulating metabolite may contribute to cardiometabolic, dairy food intake by regulating intestinal microbial characteristics and associated circulating metabolite may contribute to heart metabolism, willow Knife

This study included 1780 participants from Guangzhou Nutrition and Health Research.

There is a significant overall difference in the structure of the gut microbial community between the highest and lowest categories of total dairy products, milk and yogurt (P <0.

The microbial and α-diversity index associated with dairy products is inversely proportional to triglycerides in the blood, and directly proportional to high-density lipoprotein cholesterol .

Changes in the structure of the gut microbial community represented by the PCoA diagram based on the Bray-Curtis distance

Changes in the structure of the gut microbial community represented by the PCoA diagram based on the Bray-Curtis distance

After adjusting for sociodemographic and life>total consumption of dairy products is positively correlated with the Shannon Diversity Index and Simpson Index (a statistical quantity describing the diversity of a community) .

The total consumption of dairy products is positively correlated with the Shannon Diversity Index and Simpson Index (a statistics describing the diversity of a community ).

After the multivariate adjustment of Model 2 or Model 3, yogurt consumption is positively correlated with Shannon's Diversity Index and Simpson Index.

The relationship between dairy-related gut microbial characteristics and cardiometabolic risk factors.

The relationship between dairy-related gut microbial characteristics and cardiometabolic risk factors.

2-Hydroxy-3-methylbutyric acid, 2-hydroxybutyric acid and L-alanine are inversely proportional to dairy microbial scores and directly proportional to triglycerides.

Researchers pointed out that the consumption of dairy products is related to the composition of gut microbes and higher α-diversity, which provides new insights into understanding the interaction of dairy products-gut microbiota and its relationship with cardiometabolic health.

references:

Multi-omics analyses reveal relationships among dairy consumption, gut microbiota and cardiometabolic health.

Multi-omics analyses reveal relationships among dairy consumption, gut microbiota and cardiometabolic health.


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