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Diabetes patients are at high risk of chronic kidney disease (CKD), and with the continuous improvement of management level in recent years, has the prevalence of CKD in this population decreased? Take a look at the latest U.
S.
data
published in the New England Journal of Medicine.
Between 2000 and 2019, the number of kidney failure patients in the United States requiring dialysis or transplantation doubled to nearly 800,000, with diabetes accounting for 47%
of them.
The incidence of CKD in people with diabetes is unknown, but these data are critical
for identifying at-risk groups, assessing the effectiveness of interventions, and the impact on health care delivery and public health.
Between 2015 and 2020, the prevalence of CKD among diabetics in the United States has declined
The investigators aimed to estimate the incidence of CKD among adults with diabetes recorded in two U.
S.
health care systems from 2015 to 2020 [the Center for Research, Education, and Hope in Kidney Disease (CURE-CKD) registry, Providence Health, and UCLA Health], and identified a total of 654,459 adults with diabetes aged ≥ 20 years, with a mean age of 61 and 55.
2%
women.
The study found that:
Native Hawaiian/other Pacific Islander patients (RR 1.
56; 95% CI 1.
38 to 1.
77), black patients (RR 1.
41; 95% CI 1.
33 to 1.
50), American Indian or Alaska Native patients (RR 1.
33; 95% CI 1.
19 to 1.
50), and Hispanic or Latino patients (RR 1.
25; 95% CI 1.
20 to 1.
30) had significantly higher rates of CKD compared with white patients; The incidence of CKD was lower in Asian patients than in white patients (RR 0.
87; 95% CI 0.
82 to 0.
92) (Figure 1).
The overall incidence of CKD decreased from 81.
6 cases/1000 person-years in 2015~2016 to 64.
0 cases/1000 person-years in 2019~2020, and similar trends
were obtained in subgroup analyses for age, race, ethnicity, and sex.
Fig.
1 Comparison of the incidence of CKD in diabetic patients of different ethnicity/ethnicity in the United States
Seize the "golden age" of CKD management: call for early detection and early intervention
The researchers say that although the incidence of CKD has declined in recent years, the status of CKD in the United States remains a concern
given the large increase in the prevalence of diabetes and its accompanying high rate of renal failure.
In addition, less than 10% of patients with early-stage kidney disease are aware of their disease, which is the most effective "golden period" to prevent disease progression, calling for early detection and early intervention
.
Compiled and arranged by Tuttle KR, Jones CR, Daratha KB, et al.
Incidence of Chronic Kidney Disease among Adults with Diabetes, 2015-2020.
N Engl J Med.
2022,387(15): 1430-1431.
DOI: 10.
1056/NEJMc2207018, PMID:36239650