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Background: Since late 2019, SARS-CoV-2 emerged as a new pathogenic microorganism, causing the COVID-19 pandemic
Background: Since late 2019, SARS-CoV-2 emerged as a new pathogenic microorganism, causing the COVID-19 pandemic
Over the past two decades, many drugs have been approved for use in people with diabetes, leading to a marked shift in medication trends
Methods: PubMed, EMBASE, Scope us and Web of Science databases were systematically searched for studies (except case reports and review articles) published up to 30 November 2021
Results: We included 61 studies (3,061,584 people) that were rated as having low risk of bias
Figure 1 Forest plot of the relationship between metformin and mortality in patients with new coronary pneumonia and type 2 diabetes
Figure 1 Forest plot of the relationship between metformin and mortality in patients with new coronary pneumonia and type 2 diabetes
Figure 2 Forest plot of the relationship between GLP-1RA and mortality in patients with new coronary pneumonia and type 2 diabetes
Figure 2 Forest plot of the relationship between GLP-1RA and mortality in patients with new coronary pneumonia and type 2 diabetes
Figure 3 Forest plot of the relationship between SGLT-2i and mortality in patients with new coronary pneumonia and type 2 diabetes
Figure 3 Forest plot of the relationship between SGLT-2i and mortality in patients with new coronary pneumonia and type 2 diabetes
Table 1 Sensitivity analysis
Figure 4 Dose-response meta-analysis between daily metformin consumption and mortality in patients with COVID-19 and diabetes
Figure 4 Dose-response meta-analysis between daily metformin consumption and mortality in patients with COVID-19 and diabetes
Conclusions: Metformin, GLP-1RA and SGLT-2i were associated with lower mortality in patients with COVID-19 and type 2 diabetes
Original source: Nguyen NN, Ho DS, Nguyen HS, et al.
Preadmission use of antidiabetic medications and mortality among patients with COVID-19 having type 2 diabetes: A meta-analysis.
Metabolism 2022 Mar 31 Preadmission use of antidiabetic medications and mortality among patients with having type 2 diabetes: A meta-analysis.
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