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Metabolism: Prehospital use of hypoglycemic agents and mortality in patients with type 2 diabetes and COVID-19

 Last Update: 2022-04-24
 Source: Internet
 Author: User

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Since the end of 2019, SARS-CoV-2, as a newly emerged pathogenic microorganism, has caused the pandemic of new coronary pneumonia
.

As of the end of November 2021, more than 257 million people worldwide have been infected with SARS-CoV-2, of which about 5.

New coronary pneumonia infection COVID-19 diabetes hypertensive blood vessels

Recently, a research article was published in Metabolism-Clinical and Experimental, an authoritative journal in the field of metabolic diseases.
The researchers aimed to compare the impact of pre-admission antidiabetic drugs on in-hospital mortality in patients with type 2 diabetes and COVID-19
.

We systematically searched PubMed, EMBASE, Scopus and Web of Science databases for studies (excluding case reports and review articles) published up to 30 November 2021
.

The researchers excluded papers on the use of antidiabetic drugs during hospitalization

We included 61 studies (3,061,584 participants), which were rated as low risk of bias
.

OR (95% CI) indicated that some drugs against covid-19-related deaths, including metformin [0.

metformin

CONCLUSIONS : Metformin, GLP-1RA and SGLT-2i were associated with lower mortality in T2DM patients with COVID-19
.

DPP-4i and insulin are associated with increased mortality

Metformin, GLP-1RA, and SGLT-2i were associated with lower mortality in patients with type 2 diabetes with COVID-19

Original source:

Nam Nhat Nguyen.

Preadmission use of antidiabetic medications and mortality among patients with COVID-19 having type 2 diabetes: A meta- analysis

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