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In the past few decades, with changes in diet and longer life span, the incidence and mortality of colorectal cancer (CRC) have been rising sharply, and CRC has now become the second most common cancer in the world
In the past few decades, with changes in diet and longer life span, the incidence and mortality of colorectal cancer (CRC) have been rising sharply, and CRC has now become the second most common cancer in the world
In healthy adults, the colon contains the densest metabolically active microbial community
However, it is difficult to integrate and compare different published data because residential areas, medical treatment and technical solutions will strongly affect the changes of human gut microbiota
However, it is difficult to integrate and compare different published data because residential areas, medical treatment and technical solutions will strongly affect the changes of human gut microbiota
Therefore, in order to better understand the mechanism of colorectal cancer and develop more effective CRC screening methods, it is necessary to clarify which of the intestinal bacteria that increase or decrease in colorectal cancer patients are actually involved in CRC.
The types of intestinal microbes enriched in patients with colorectal cancer
The types of intestinal microorganisms that are enriched in patients with colorectal cancer The types of intestinal microorganisms that are enriched in patients with colorectal cancerRecently, researchers found in two independent cohort studies that 12 taxa of fecal bacteria were enriched in CRC patients
Recently, researchers found in two independent cohort studies that 12 taxa of fecal bacteria were enriched in CRC patients
It is worth noting that the invasion of these bacteria was observed in CRC tissue, which is consistent with the increase in butyrate levels and the signs of aging-related inflammation
Therefore, these results collectively indicate that there is a causal relationship between the overgrowth of Porphyromonas and the occurrence of colorectal tumors, which may be due to butyrate-induced senescence
Original source:
Original source: Original source:Shintaro Okumura et al.
Shintaro Okumura et al.
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