NAT MED: "Human pig complex" can help restore damaged human lungs

!---- Patients waiting for a lung transplant face a higher waiting list mortality rate because the injury makes most donor lungs unusableAlthough in vitro pulmonary perfusion (EVLP) restores marginal mass donor lungs, extending room temperature support to more than 6 hours has been challengingrecently, researchers have shown that acute damage to human lungs that cannot be performed on lung transplants, including those that are not recovered on EVLP, can be recovered through the full blood cross-circulation between the implanted human lungs and the Yorkshire pigthis heterogeneous gene platform provides a supportive physiological environment and system regulation for the exosome human lung, leading to functional and histological recovery after 24-hour room temperature supportthe results of this study, cross-circulation can be used as a complementary method of clinical EVLP to restore the injured donor lung, as well as as as a transformational research platform for immunomodulation and advanced organ bioengineering