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High-protein calorie restriction diet has a clinical effect on obesity, but its mechanism is not fully understood
.
The gut microbiome is a vector of obesity.
In order to solve this problem, the researchers conducted a diet intervention trial on 80 overweight and obese subjects, who were randomly assigned to a calorie-restricted high-protein diet (HPD) (30% calorie intake) or a calorie-restricted normal protein diet (NPD) (15%) 8 weeks
.
Use the Diet History Questionnaire III to assess the baseline dietary intake pattern
The results showed that at baseline, microbial composition was related to fiber and protein intake
.
Compared with subjects with NPD, subjects with HPD showed a significant increase in microbial diversity
Taken together, these findings provide evidence that weight loss diet changes the gut microbiome of obesity, and show that HPD has a different effect compared to NPD, which may affect the clinical response of HPD
Original source:
Tien S Dong, et al.
A High Protein Calorie Restriction Diet Alters the Gut Microbiome in Obesity in this message
