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Introduction: Type 2 diabetes deserves everyone's attention, especially young people! In recent years, coronary heart disease has gradually become younger.
According to data released by the National Health Commission, from 2007 to 2009, the incidence of acute myocardial infarction among people over 25 years of age has increased year by year, especially among people aged 35 to 44, which has increased the most in three years.
31.
8%.
In January of this year, Sun Qiaolu, the actor of "Ballala Little Devil" Ling Meiqi, passed away.
The cause of death was suspected to be a sudden cardiac infarction.
He was only 25 years old.
Recalling a year ago, 35-year-old male star Gao Yixiang passed away due to sudden cardiac death, which aroused public attention.
Why does coronary heart disease frequently target young people? The World Health Organization divides coronary heart disease into five major categories: myocardial infarction, sudden death, angina pectoris, silent myocardial ischemia, and ischemic heart failure.
Researchers from Brigham and Women’s Hospital and Mayo Clinic found that a new biomarker of insulin resistance (LPIR) is associated with a 600% increase in the risk of premature coronary heart disease.
Women with type 2 diabetes under the age of 55 have a higher risk of coronary heart disease.
Increase tenfold.
The results of the study will be published in "JAMA Cardiology" on January 20, 2021.
Association of Lipid, Inflammatory, and Metabolic Biomarkers With Age at Onset for Incident Coronary Heart Disease in Women.
2.
DOI: 10.
1001/jamacardio.
2020.
7073 This study is a prospective cohort study involving 28,024 women over 45 years of age.
The median follow-up time was 21.
4 years.The researchers divided the participants into 4 age groups (<55, 55 to <65, 65 to <75 and ≥75 years old) according to the age of onset of coronary heart disease.
The evaluation indicators have more than 50 clinical, lipid, inflammatory and metabolic risk factors and biomarkers.
Researchers used a stratified Cox proportional hazard regression model to calculate adjusted hazard ratios (aHRs).
The results of the study found that among about 50 biomarkers, compared with commonly known markers such as low-density lipoprotein (LDL) cholesterol (or "bad" cholesterol) and hemoglobin A1C (blood sugar level), insulin resistance is new Biomarkers (LPIR) are associated with a 600% increase in the risk of premature coronary heart disease, while low-density lipoprotein cholesterol is only associated with a 40% increase in the risk of CHD.
Lipoprotein insulin resistance (LPIR) is a powerful predictive biomarker.
The (LPIR) score is composed of six lipoprotein parameters determined by nuclear magnetic resonance spectroscopy.
Correlation between different lipid indicators and CHD at different ages Correlation between inflammatory indicators and CHD at different ages Among clinical factors, diabetes has the highest proof-reading risk ratio (aHR) of coronary heart disease! The incidence ranges from 10.
71 for those under 55 years of age to 3.
47 for those over 75 years of age.
Risk factors for coronary heart disease in participants under 55 years of age also included metabolic syndrome (aHR, 6.
09), hypertension (4.
58), obesity (4.
33), and smoking (3.
92).
The correlation between clinical risk factors and lipid biomarkers and the occurrence of CHD at different ages.
Therefore, in this cohort study, insulin resistance, type 2 diabetes and its metabolic syndrome are the main causes of premature coronary artery onset.
In addition, obese women under the age of 55 have a four-fold increased risk of coronary artery disease, as do women who smoke or suffer from high blood pressure in this age group.
This study suggests the need for early cardiovascular risk monitoring and assessment for young diabetic patients.
Screening and proper prediabetes management may contribute to the primary and secondary prevention of cardiovascular disease.
Diabetes (DM) is considered by the World Health Organization (WHO) as one of the four major non-communicable diseases.
According to the 2019 data of the International Diabetes Federation (IDF), by 2045, the number of people with diabetes worldwide will increase by 51% to 700 million.
In my country, the overall prevalence has been increasing since the 1970s, with the highest prevalence in Northeast China.
idf.
org The prevalence of T2DM in geographic areas.
Trends in subgroup analysis by geographic area.
The darker the color, the higher the prevalence.
Prevalence of type 2 diabetes mellitus among inland residents in China (2000-2014): A meta-analysis.
DOI: 10.
1111/jdi.
12514 It is worth noting that diabetes is becoming more and more Younger, the global incidence of diabetes diagnosed before the age of 40 is increasing.
In Asia, one-fifth of diabetes patients belong to the young-onset population.
Family inheritance and obesity are the main reasons for the onset of diabetes in young patients.
The hospitalization rate and mortality rate of young people with diabetes are higher.
On November 12, 2020, "The Lancet" released a blockbuster report.
In this report, experts emphasized the impact that cannot be ignored due to the rejuvenation of diabetes.
Young-onset diabetes refers to the diagnosis of diabetes before the age of 40.
In this report, research shows that compared with elderly diabetic patients, the mortality rate of young diabetic patients is higher! The Lancet Commission on diabetes: using data to transform diabetes care and patient livesdoi: 10.
1016/S0140-6736(20)32374-6.
Epub 2020 Nov 12 By age and country, compared with the general population, the all-cause mortality of diabetes patients These experimental results make every young person pay more attention to diabetes.
How to prevent diabetes in daily life? A systematic review report published in BMJ showed that eating more whole grains and adhering to a healthy diet will reduce the incidence of type 2 diabetes, while eating more total red meat, processed meat, and sugar Drinks will increase the incidence.
(For more information on healthy diet, please refer to the previous article: Pro-inflammatory diet and anti-inflammatory diet, how much do you know?) What are the recommendations for diabetic patients? According to the "National Handbook for the Prevention and Management of Diabetes at the Primary Level (2019)", lifestyle intervention, namely exercise and diet, should be considered at the early stage of diabetes diagnosis; if lifestyle intervention does not meet the blood sugar standard, drug treatment should be started.
A randomized controlled study published in The Lancet Diabetes showed that in the early stage of diabetes (within 3 years), participants were provided with formula low-energy meal replacement products, and then gradually reintroduced food and combined with physical activity support.
After 12 months of treatment, it can significantly reduce weight and improve blood sugar levels.
The average weight of the intervention group was reduced by 11.
98kg.
More than 60% of the participants had remission of diabetes, and more than 30% had normal blood sugar.
Effectof intensive lifestyle intervention on bodyweight and glycaemia in early type 2diabetes (DIADEM-I): an open-label, parallel-group, randomised controlledtrial.
The Lancet Diabetes & Endocrinology, 8(6), 477–489.
doi:10.
1016/s2213 -8587(20)30117-012 Participants' weight changes within 12 months The proportion of participants who reached the key weight loss goal within 12 months.
Intensified lifestyle interventions can improve the cardiometabolic outcomes of most young people with early diabetes, and have potential long-term health benefits.
In short, for coronary heart disease and type 2 diabetes, prevention is better than cure.
A healthy lifestyle is the key to preventing chronic diseases.
In this beautiful spring day, I hope that every reader will be healthy, joyful and happy.
Attention! Dear Metz Medicine readers want to participate in more discussions? Get information in the field of cardiovascular medicine the first time? Then join the Metz Medical Cardiovascular Exchange Group immediately~Come~ Scan the QR code to join the group! ! ! Source: Metz Medical Comprehensive Report authorized to reprint, submit articles and break the news.
Please contact Metz Medical Administrator MedSci (WeChat ID: medsci_m) to recommend reading tea that has been drunk for thousands of years.
Is it cancer-proof or carcinogenic? China's smog again tops the list, and exposure to the hazards for 24 hours will accompany you for a lifetime! If you want to know more information, please click to read the original text to download the Metz Medical APP~ Share to the circle of friends, so that more friends can see!
According to data released by the National Health Commission, from 2007 to 2009, the incidence of acute myocardial infarction among people over 25 years of age has increased year by year, especially among people aged 35 to 44, which has increased the most in three years.
31.
8%.
In January of this year, Sun Qiaolu, the actor of "Ballala Little Devil" Ling Meiqi, passed away.
The cause of death was suspected to be a sudden cardiac infarction.
He was only 25 years old.
Recalling a year ago, 35-year-old male star Gao Yixiang passed away due to sudden cardiac death, which aroused public attention.
Why does coronary heart disease frequently target young people? The World Health Organization divides coronary heart disease into five major categories: myocardial infarction, sudden death, angina pectoris, silent myocardial ischemia, and ischemic heart failure.
Researchers from Brigham and Women’s Hospital and Mayo Clinic found that a new biomarker of insulin resistance (LPIR) is associated with a 600% increase in the risk of premature coronary heart disease.
Women with type 2 diabetes under the age of 55 have a higher risk of coronary heart disease.
Increase tenfold.
The results of the study will be published in "JAMA Cardiology" on January 20, 2021.
Association of Lipid, Inflammatory, and Metabolic Biomarkers With Age at Onset for Incident Coronary Heart Disease in Women.
2.
DOI: 10.
1001/jamacardio.
2020.
7073 This study is a prospective cohort study involving 28,024 women over 45 years of age.
The median follow-up time was 21.
4 years.The researchers divided the participants into 4 age groups (<55, 55 to <65, 65 to <75 and ≥75 years old) according to the age of onset of coronary heart disease.
The evaluation indicators have more than 50 clinical, lipid, inflammatory and metabolic risk factors and biomarkers.
Researchers used a stratified Cox proportional hazard regression model to calculate adjusted hazard ratios (aHRs).
The results of the study found that among about 50 biomarkers, compared with commonly known markers such as low-density lipoprotein (LDL) cholesterol (or "bad" cholesterol) and hemoglobin A1C (blood sugar level), insulin resistance is new Biomarkers (LPIR) are associated with a 600% increase in the risk of premature coronary heart disease, while low-density lipoprotein cholesterol is only associated with a 40% increase in the risk of CHD.
Lipoprotein insulin resistance (LPIR) is a powerful predictive biomarker.
The (LPIR) score is composed of six lipoprotein parameters determined by nuclear magnetic resonance spectroscopy.
Correlation between different lipid indicators and CHD at different ages Correlation between inflammatory indicators and CHD at different ages Among clinical factors, diabetes has the highest proof-reading risk ratio (aHR) of coronary heart disease! The incidence ranges from 10.
71 for those under 55 years of age to 3.
47 for those over 75 years of age.
Risk factors for coronary heart disease in participants under 55 years of age also included metabolic syndrome (aHR, 6.
09), hypertension (4.
58), obesity (4.
33), and smoking (3.
92).
The correlation between clinical risk factors and lipid biomarkers and the occurrence of CHD at different ages.
Therefore, in this cohort study, insulin resistance, type 2 diabetes and its metabolic syndrome are the main causes of premature coronary artery onset.
In addition, obese women under the age of 55 have a four-fold increased risk of coronary artery disease, as do women who smoke or suffer from high blood pressure in this age group.
This study suggests the need for early cardiovascular risk monitoring and assessment for young diabetic patients.
Screening and proper prediabetes management may contribute to the primary and secondary prevention of cardiovascular disease.
Diabetes (DM) is considered by the World Health Organization (WHO) as one of the four major non-communicable diseases.
According to the 2019 data of the International Diabetes Federation (IDF), by 2045, the number of people with diabetes worldwide will increase by 51% to 700 million.
In my country, the overall prevalence has been increasing since the 1970s, with the highest prevalence in Northeast China.
idf.
org The prevalence of T2DM in geographic areas.
Trends in subgroup analysis by geographic area.
The darker the color, the higher the prevalence.
Prevalence of type 2 diabetes mellitus among inland residents in China (2000-2014): A meta-analysis.
DOI: 10.
1111/jdi.
12514 It is worth noting that diabetes is becoming more and more Younger, the global incidence of diabetes diagnosed before the age of 40 is increasing.
In Asia, one-fifth of diabetes patients belong to the young-onset population.
Family inheritance and obesity are the main reasons for the onset of diabetes in young patients.
The hospitalization rate and mortality rate of young people with diabetes are higher.
On November 12, 2020, "The Lancet" released a blockbuster report.
In this report, experts emphasized the impact that cannot be ignored due to the rejuvenation of diabetes.
Young-onset diabetes refers to the diagnosis of diabetes before the age of 40.
In this report, research shows that compared with elderly diabetic patients, the mortality rate of young diabetic patients is higher! The Lancet Commission on diabetes: using data to transform diabetes care and patient livesdoi: 10.
1016/S0140-6736(20)32374-6.
Epub 2020 Nov 12 By age and country, compared with the general population, the all-cause mortality of diabetes patients These experimental results make every young person pay more attention to diabetes.
How to prevent diabetes in daily life? A systematic review report published in BMJ showed that eating more whole grains and adhering to a healthy diet will reduce the incidence of type 2 diabetes, while eating more total red meat, processed meat, and sugar Drinks will increase the incidence.
(For more information on healthy diet, please refer to the previous article: Pro-inflammatory diet and anti-inflammatory diet, how much do you know?) What are the recommendations for diabetic patients? According to the "National Handbook for the Prevention and Management of Diabetes at the Primary Level (2019)", lifestyle intervention, namely exercise and diet, should be considered at the early stage of diabetes diagnosis; if lifestyle intervention does not meet the blood sugar standard, drug treatment should be started.
A randomized controlled study published in The Lancet Diabetes showed that in the early stage of diabetes (within 3 years), participants were provided with formula low-energy meal replacement products, and then gradually reintroduced food and combined with physical activity support.
After 12 months of treatment, it can significantly reduce weight and improve blood sugar levels.
The average weight of the intervention group was reduced by 11.
98kg.
More than 60% of the participants had remission of diabetes, and more than 30% had normal blood sugar.
Effectof intensive lifestyle intervention on bodyweight and glycaemia in early type 2diabetes (DIADEM-I): an open-label, parallel-group, randomised controlledtrial.
The Lancet Diabetes & Endocrinology, 8(6), 477–489.
doi:10.
1016/s2213 -8587(20)30117-012 Participants' weight changes within 12 months The proportion of participants who reached the key weight loss goal within 12 months.
Intensified lifestyle interventions can improve the cardiometabolic outcomes of most young people with early diabetes, and have potential long-term health benefits.
In short, for coronary heart disease and type 2 diabetes, prevention is better than cure.
A healthy lifestyle is the key to preventing chronic diseases.
In this beautiful spring day, I hope that every reader will be healthy, joyful and happy.
Attention! Dear Metz Medicine readers want to participate in more discussions? Get information in the field of cardiovascular medicine the first time? Then join the Metz Medical Cardiovascular Exchange Group immediately~Come~ Scan the QR code to join the group! ! ! Source: Metz Medical Comprehensive Report authorized to reprint, submit articles and break the news.
Please contact Metz Medical Administrator MedSci (WeChat ID: medsci_m) to recommend reading tea that has been drunk for thousands of years.
Is it cancer-proof or carcinogenic? China's smog again tops the list, and exposure to the hazards for 24 hours will accompany you for a lifetime! If you want to know more information, please click to read the original text to download the Metz Medical APP~ Share to the circle of friends, so that more friends can see!
