Pharm Biol: Effects of leeks and rapeseed oil on the oxidation metabolism of neutrophils in obese patients

Leek oil and low mustard rapeseed oil are often usedBecause of its outstanding nutritional value, leeks have attracted much attentionLeek oil is a rich source of high unsaturated fats, so it may be a valuable dietary alternative for obese peopleIt is assumed that reactive oxygen (ROS) is involved in systemic inflammation and oxidative stressActivated polymorphic nuclear neutrophils (PMNs) produce large amounts of reactive oxygenThis study investigated the effects of leeks and low mustard rapeseed oil supplements on oxidative metabolism in obese patientsWe hypothesize that because canola oil and low mustard rapeseed oil have a lipid-lowering and antioxidant effect, they can resist oxidative stresswe tested 19 obese patients in a body mass index (BMI) of 41.1 to 7.8 kg / m2, (average sD).) The program consists of two phases: a two-week run-in period and an experimental phase - a low mustard rapeseed or canola oil supplement (20 mL / d) on a calorie-limiting diet for 3 weeksThe oxidation of neutrophils is represented by fluorescence intensity (IF)results showed that at the end of both groups of IF treatment, the oxidation outbreaks increased significantly: (21.4 x 11.15 vs35.9 x 20.3; average sD) p .05The IF level of neutrophils treated with low mustard rapeseed oil (41.05 to 25.3) was significantly higher than the p.05 in patients receiving leek oil (28.4 x 11.8), the results show that canola seed oil in the body can affect the activity of oxidation in neutrophils