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Background: Understanding the acute and long-term health effects of radiation exposure is critical for developing effective countermeasures to prevent adverse health effects following radiation exposure
.
The health of those exposed in the prenatal and early postnatal period is of particular concern
The health of those exposed in the prenatal and early postnatal period is of particular concern
MATERIALS AND METHODS: Thyroid screening tests currently performed routinely, including thyroid palpation, ultrasonography, blood samples to diagnose hypothyroidism and hyperthyroidism, autoimmune thyroiditis, thyroid function tests (thyroid stimulating hormone [TSH], thyroxine [T4], thyroid peroxidase antibody [anti-TPO], thyroglobulin antibody [anti-TG])
.
(i) Questionnaire information was obtained at the first and second follow-up visits of 780 mothers, and (ii) thyroid doses were calculated for cohort members using this information, and their reliability was assessed
RESULTS: As of August 15, 2021, 1267 uterine exposure study subjects had been screened
.
There were 167 cases of single thyroid nodules (13.
Figure 1.
Geographical distribution of Belarusian in utero cohort members according to maternal residence and 131I deposition density at the time of Chernobyl
.
Geographical distribution of Belarusian in utero cohort members according to maternal residence and 131I deposition density at the time of Chernobyl
.
Table 1 Pathology of thyroid nodules detected before and during screening
Table 1 Pathology of thyroid nodules detected before and during screeningTable 2 Estimated subject thyroid dose by different exposure routes
Table 2 Estimated subject thyroid dose by different exposure routesTable 3 Consistency of responses in two individual interviews by mothers of 780 Belarusian intrauterine cohort members
Table 3 Consistency of responses in two individual interviews by mothers of 780 Belarusian intrauterine cohort membersFigure 2 Comparison of model-based prenatal THY=ROID doses due to 131I CAL calculated using information from the first and second interviews
.
.
Conclusions: During thyroid screening, at least one thyroid nodule was found in 268 (21.
2%) of 1267 uterine-exposed cohort members
.
Seven thyroid cancer cases were identified in the cohort, including 5 prescreening cases and 2 screening cases
During thyroid screening, at least one thyroid nodule was found in 268 (21.
THYROID SCREENING AND RELIABILITY OF RADIATION THYROID DOSES FOR THE BELARUSIAN IN UTERO COHORT.
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