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12, 2020 // -- In a recent study published in the international journal Circust Research, scientists from the University of Otago and others revealed how exercise can help reduce the risk of heart disease caused by diabetes, suggesting that exercise can induce the release of microRNAs in the heart, which can help increase protein production and help improve heart structure and function.
Photo Source: Professor Daryl Schwenke, a researcher at Pixabay/CC0 Public Domain, says this particular microRNA can change adversely in the early stages of diabetes, and that these changes in microRNA can reliably help predict heart attacks.
Now researchers have found that exercise can increase the production of good microRNAs and reduce the effects of bad microRNAs on the health of the body, and that exercise can help inhibit the occurrence and progression of heart disease by improving the regulation of microRNAs.
emphasizing the key role exercise plays in regulating microRNA function, the results of this paper also suggest that microRNA can be a new target to help scientists develop new treatments for heart disease in chronic diabetics.
researchers point out that the use of pharmacological drugs to increase or effectively reduce the risk of heart disease in people with diabetes does not appear to depend on exercise, and that more than 250,000 New Zealanders currently have diabetes, making the disease a serious health challenge for the public.
study has significant long-term benefits for improving the quality of life of people with diabetic heart disease and reducing the financial burden on patients with current diabetes treatment.
, the researchers say that by understanding the physiological role played by microRNAs, scientists may be able to determine the important role exercise plays in preventing diabetic heart disease.
original source: Jason Kar-Sheng Lew, James T Pearson, Eugene Saw, et al. Exercise Regulates microRNAs to Preserve Coronary and Cardiac Function in The Diabetic Heart, Issue Research (2020). DOI:10.1161/CIRCRESAHA.120.317604.
