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The prognosis of prostate cancer (PCa) patients depends to a large extent on the presence of metastases and the amount of metastases at the initial onset
Recently, researchers from the Netherlands published an article in "Prostate Cancer PD", evaluating the effects of preoperative prostate-specific membrane antigen (PSMA) PET/CT on robot-assisted radical prostatectomy (RARP) + extended pelvic LN dissection (ePLND).
Evaluated the prediction of preoperative prostate-specific membrane antigen (PSMA) PET/CT for robot-assisted radical prostatectomy (RARP) + extended pelvic LN dissection (ePLND) for biochemical persistence (BCP) and early biochemical recurrence (BCR) The value of preoperative prostate-specific membrane antigen (PSMA) PET/CT was evaluated for the effect of robot-assisted radical prostatectomy (RARP) + extended pelvic LN dissection (ePLND) on the biochemical persistence (BCP) and early biochemical recurrence (BCR) Predictive value
The study evaluated 213 middle- and high-risk prostate cancer (PCa) patients who were clinically staged by 68Ga- or 18F-PSMA-PET/CT scans before surgery, followed by RARP and ePLND
diagnosis
The results of the study found that 40 patients (19%) had PSMA+
PSMA+ is an important predictor of BCP (OR 7.
Univariate logistic regression of BCP and BCR predictors
Univariate logistic regression of BCP and BCR predictorsIn summary, preoperative PSMA-PET/CT is an important tool for predicting the risk of BCP and early BCR after surgery, and can provide valuable information for patients treated with RARP+ePLND
Preoperative PSMA-PET/CT is an important tool for predicting the risk of BCP and early BCR after surgery.
Original source:
DJH Baas, M.
Preoperative PSMA-PET/CT as a predictor of biochemical persistence and early recurrence following radical prostatectomy with lymph node dissection.
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