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    Home > Active Ingredient News > Antitumor Therapy > Prostate Cancer PD: Preoperative PSMA-PET/CT of prostate cancer can be used as a predictor of persistent and early recurrence of postoperative biochemistry

    Prostate Cancer PD: Preoperative PSMA-PET/CT of prostate cancer can be used as a predictor of persistent and early recurrence of postoperative biochemistry

    • Last Update: 2021-09-18
    • Source: Internet
    • Author: User
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    The prognosis of prostate cancer (PCa) patients depends to a large extent on the presence of metastases and the amount of metastases at the initial onset


    Recently, researchers from the Netherlands published an article in "Prostate Cancer PD", evaluating the effects of preoperative prostate-specific membrane antigen (PSMA) PET/CT on robot-assisted radical prostatectomy (RARP) + extended pelvic LN dissection (ePLND).


    Evaluated the prediction of preoperative prostate-specific membrane antigen (PSMA) PET/CT for robot-assisted radical prostatectomy (RARP) + extended pelvic LN dissection (ePLND) for biochemical persistence (BCP) and early biochemical recurrence (BCR) The value of preoperative prostate-specific membrane antigen (PSMA) PET/CT was evaluated for the effect of robot-assisted radical prostatectomy (RARP) + extended pelvic LN dissection (ePLND) on the biochemical persistence (BCP) and early biochemical recurrence (BCR) Predictive value

    The study evaluated 213 middle- and high-risk prostate cancer (PCa) patients who were clinically staged by 68Ga- or 18F-PSMA-PET/CT scans before surgery, followed by RARP and ePLND


    diagnosis

    The results of the study found that 40 patients (19%) had PSMA+


    PSMA+ is an important predictor of BCP (OR 7.


    Univariate logistic regression of BCP and BCR predictors

    Univariate logistic regression of BCP and BCR predictors

    In summary, preoperative PSMA-PET/CT is an important tool for predicting the risk of BCP and early BCR after surgery, and can provide valuable information for patients treated with RARP+ePLND


    Preoperative PSMA-PET/CT is an important tool for predicting the risk of BCP and early BCR after surgery.


    Original source:

    DJH Baas, M.


    Preoperative PSMA-PET/CT as a predictor of biochemical persistence and early recurrence following radical prostatectomy with lymph node dissection.




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