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    Home > Active Ingredient News > Immunology News > Rheumatology: Systemic lupus erythematosus disease activity affects neurological and behavioral cognition

    Rheumatology: Systemic lupus erythematosus disease activity affects neurological and behavioral cognition

    • Last Update: 2021-04-13
    • Source: Internet
    • Author: User
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    Many common factors in chronic diseases, such as fatigue and depression, affect cognitive dysfunction (CD), but the impact of systemic lupus erythematosus (SLE) disease activity on CD is unclear.


    The study selected two groups of patients with systemic lupus erythematosus: stable phase/low activity phase (SLE-S, n = 36 cases) and active phase (SLE-F, n = 26 cases).


    Analysis of BOLD signal difference during n-back task between SLE-S and SLE-Fv1

    Analysis of BOLD signal difference during n-back task between SLE-S and SLE-Fv1

    Changes of BILAG scores in SLE-F group twice

    Changes of BILAG scores in SLE-F group twice

    When using the CANTAB® test, no differences were found between the two groups.


    Many factors affect the cognitive function of SLE.


    Many factors affect the cognitive function of SLE.


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    com/rheumatology/advance-article-abstract/doi/10.
    1093/rheumatology/keab256/6184875?redirectedFrom=fulltext" target="_blank" rel="noopener">Barraclough, Michelle et al.
    “The effects of disease activity on neuronal and behavioural cognitive processes in systemic lupus erythematosus.
    ”Rheumatology (Oxford, England) , keab256.
    24 Mar.
    2021, doi:10.
    1093/rheumatology/keab256 Barraclough, Michelle et al "The effects of disease activity on neuronal and behavioural cognitive processes in systemic lupus erythematosus.
    "Rheumatology (Oxford, England) leave a message here
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