Sci Adv: Multiple intake of saturated fatty acids can help relieve pancreatitis

February 3, 2021 /--- A team of researchers from the Mayo Clinic, St. Louis University School of Medicine and Washington University School of Medicine found evidence that people who ate saturated fat foods may have fewer symptoms if they had pancreatitis.
the team described the comparison of pancreatitis patients and their dietary data in a paper published in the journal Science Advance.
for more than a year, medical scientists have been tried to address the obesity paradox, in which some obese patients are treated better in some cases than non-obese patients.
new experiment, researchers are trying to better understand why this sometimes happens by focusing on pancreatitis.
previous studies have shown that pancreat.com itis can be triggered by a variety of events, such as abdominal surgery or excessive drinking.
previous studies have also shown that obese people are more likely to develop pancreatitis, although it is not clear why.
the new study, researchers looked closely at the link between pancreatitis and fat intake (saturated or unsaturated).
saturated fats are found mainly in meat, butter, cheese and other foods, while unsaturated fats are found mainly in plants and fish.
previous studies have shown that people are healthier if they reduce their intake of saturated fat and eat more unsaturated fat.
to learn more about the link between eating different types of fat and pancreatitis, the researchers studied data from 20 clinical reports from 11 countries that monitored fat consumption in obese patients.
researchers found that people with high levels of saturated fat also suffered from pancreatitis, but with milder symptoms, compared to those with high levels of unsaturated fat in their diet.
their findings caught their interest, and the team experimented with experimental mice - some of which were fed a diet rich in saturated and other unsaturated fats - and then they caused pancreatitis in all mice.
found that mice fed saturated fat had less severe symptoms.
close inspection, they found poor interaction between saturated fat and triglyceride lipase in the pancreas, which led to a reduction in the production of long-chain non-esterified fatty acids and reduced symptoms of pancreatitis.
(Bioon.com) Source: Eating saturated fats found to reduce severity of pancreatitis Source: Biswajit Khatua et al. Adipose saturation reduces lipotoxic systemic inflammation and explains the obesity paradox, Science Advances (2021). DOI: 10.1126/sciadv.abd6449