Sci Rep: Systemic lupus gastrointestinal strain

Systemic lupus (SLE) gastrointestinal (GI) complications are characterized by multiple segments and multiple organ fatigueThe aim of the study was to create a system based on computer tomography (CT) images for disease assessmentstudy retrospectively included in accompanying GI-affected SLE patients from two separate cohortsAt the baseline, each patient underwent an abdominal CT scan of the vein and oral contrast agentEstablish and validate the CT scoring system, which includes the degree of GI wear, the thickness of the intestinal wall, and the weariness of the external organs of GIThe outcome indicator is the time at which GI function is restored, defined as the time that can be tolerated by the intake of 50% of the ideal calories (PO50)54 and 37 SLE patients with GI-affected injuries were included in the deduction and validation queuesThe CT score of SLE GI's affected ness was positively correlated with the time the patient reached PO50 (r?0.57, p 0.0001, derived queue; r?0.42, p-0.0093, validation queue)Patients with a CT score of 3 in the summary queue reached PO50 for a short period of time (median time of 0 days), while patients with CT score of 3 reached the median of PO50 significantly extended to 13 days (p 0.0001)CT-based scoring system helps to more accurately evaluate and personalize treatment of GI-affected SLE patients