Scientists may be able to use gut microbes to develop preventive and therapeutic measures for type 2 diabetes.

29, 2020 /PRNewswire/ -- In a recent study published in the international journal Cell Metabolism entitled "The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study", scientists from institutions such as the University of Gothenburg have shown that gut microbes may provide valuable clues to the treatment of diabetes.
researchers say that by studying the microbiome in habits in the human gastrointestinal tract or by helping to predict an individual's future risk of type 2 diabetes, it can make type 2 diabetes predictable, preventable and timely to take action to treat it.
previous study, researchers found that gut microbes promote type 2 diabetes, and in this study, researchers found key clues in gut microbes that may shed light on how microbes induce type 2 diabetes and how to predict whether they will develop type 2 diabetes in the future based on the characteristics of gut microbes in an individual body.
photo source: CC0 Public Domain's study of people with type 2 diabetes, researchers can rule out the possibility of intestinal microbes affected by disease or therapy, after most studies in this area compared healthy people with type 2 diabetes patients;
, the researchers also found that in the study of pre-diabetes or type 2 diabetes patients in the body's gut microbes, the ability to produce microbe butyrate is a special fatty acid, which promotes the production of hormones in the gastrointestinal tract and can help control the body's inflammation; One possible significance of fiber digestion is to be able to alter an individual's intake of fiber, or to match the type of fiber to a particular gut microbe, or to help researchers develop a new generation of probiotics to increase the number of bacteria missing in the individual body, which may help scientists develop new preventive diabetes strategies or therapeutic measures. The results of this paper clearly suggest that the composition of gut microbes may potentially help to understand the individual's risk of type 2 diabetes, as well as improve the chances of scientists detecting, preventing and treating type 2 diabetes, said Backhed, a
researcher.
the results of this paper confirm the interaction between gut microbes and organic function and internal conditions, the intestine contains more than one kilogram of bacteria that is very important to the health of the body, and the type of intestinal flora of the body of type 2 diabetes patients may not be the same as in the health population.
researchers hope that by studying specific patterns and identifying specific components in gut microbes that can help identify individuals at increased risk of type 2 diabetes, future researchers may be able to develop personalized dietary change strategies, or new types of probiotics to prevent or even treat people with type 2 diabetes.
the study, based on a large population-based study conducted by researchers in 2013 that included 5,000 randomly selected participants who investigated which factors increased an individual's risk of developing type 2 diabetes, and in order to confirm and validate the results, the researchers needed to conduct an in-depth analysis of the samples collected.
the final researchers say they will continue to delve into the details of how to specifically use gut microbes to develop preventive and therapeutic measures for type 2 diabetes.
() References: 1. Gut microbiota provide clues for treating diabetes s2, Hao Wu, Valentina Tremaroli, Caroline Schmidt, et al. The Gut Microbiota in Prediabetes and Diabetes: A-Population-Based Cross-Sectional Study, Cellsm (2020). doi: 10.1016/j.cmet.2020.06.011.